American Brain Foundation’s Post

#1 our NATURE Journal publications. Principles of microcircuit Neuron was published in NATURE Journal. The highest Impact Factors (69.504) Scientific International Journal. Our findings define the microcircuit changes initiating competitive plasticity during critical periods of cortical developmen & disinhibitory microcircuit initiates critical period plasticity. The discovery is very important to understand many brain disorders. https://lnkd.in/g4HsTyM

Postdoctoral scholar Keundong Lee is one of the first authors on a recent Nature Communications paper describing a new way to manufacture deep brain electrodes. He shares how he got involved with the project, his work over the past years in the UC San Diego research group of Professor Shadi Dayeh, and his hopes for the device, in this video. These electrodes allow minimally-invasive, high-resolution recording as deep as 4 inches inside the human brain. This technology is a first step towards wireless monitoring of patients with treatment-resistant epilepsy for extended periods of time–up to 30 days–as they go about their daily lives. Beyond treatment-resistant epilepsy, the potential applications are much broader, including helping people with Parkinson’s disease, movement disorders, obsessive-compulsive disorder, obesity, treatment-resistant depression, high-impact chronic pain and other disorders. Learn more about this research here: https://lnkd.in/gxgreq9v

This Week in Science (16 - 22 June) 🧪 New possible treatment for polycystic ovary syndrome, lots of incredible neurological research, a new upper limit for light speed, and more! Full articles 📖 PCOS treatment: https://bit.ly/4bdJqo4 Brain scans: https://bit.ly/4bdJq7y Light weight: https://bit.ly/3zbTlNw Brain complexity: https://bit.ly/4cxSzIS Autism DNA: https://bit.ly/4cwMlZV Tool usage: https://bit.ly/4ce3Cax

There is a wide range of neurological disorders and diseases, and they are exceedingly difficult to treat. One of these neurological diseases is ALS. Toffler Scholar Yingzhi Ye is part of a team studying a pathological protein found in ALS patients in hopes of learning why it is mass-localized in those patients. The team is also investigating the physiological and pathological functions of this protein in neurons. Ye’s research examines a protein found in human postmortem tissue and is disordered in a way that causes it to accumulate and clump together. The pathological protein is found in up to 90% of cases of ALS. Ye and fellow investigators want to find the target that can rescue the loss of function of this protein. Learn more about her research: https://lnkd.in/gy4b8PVx #TofflerScholar #MedicalResearch

The New Stress Cure? A new Northwestern Medicine study has found that we could release endogenous (the body's own) cannabinoid molecules under stress. They have just studied mice and found this is what they do. The key emotional brain centre for them and us, the amygdala, releases cannabinoid molecules under stress that dampens the incoming stress alarm from the memory part of our brain, the hippocampus. The finding may reveal novel therapeutic targets for the treatment of stress-related disorders. The learning for now? Know that there is more within you to fight the stresses that exist in your life and that nothing is more important than keeping your health in check. 

Informed decision making in MS, and the striatum in neurodegeneration What’s the role of the striatum, in changes in cognition and behaviour in neurodegeneration? Michael Hornberger, University of Cambridge, explains why it may be more pivotal than we currently think. And how best to support patients just diagnosed with multiple sclerosis, who are facing difficult decisions around their treatment? Sascha Köpke, University of Lübeck, discusses the results of his trial comparing two programmes. Read the papers, for free: Beyond and below the cortex: the contribution of striatal dysfunction to cognition and behaviour in neurodegeneration http://goo.gl/IZJi2o Evidence-based patient information programme in early multiple sclerosis: a randomised controlled trial http://goo.gl/nQdJ15 Source by … Read More » What’s the role of the striatum, in changes in cognition and behaviour in neurodegeneration? Michael Hornberger, University of Cambridge, explains why it may be more pivotal than we currently think. And how best to support patients just diagnosed with multiple sclerosis, who are facing difficult decisions around their treatment? Sascha Köpke, University of Lübeck, discusses the results of his trial comparing two programmes. Read the papers, for free: Beyond and below the cortex...

"Breaking new ground in neurologye research! Our latest publication in an international journal showcases cutting-edge discoveries and advancements in understanding the complexities of the brain. Proud to contribute to the global conversation on neurological health and innovation. #NeurologyResearch #InternationalPublication #AdvancingScience 🧠🔬🌍"

🏆Congrats to the National Institute of Neurological Disorders and Stroke (NINDS) Rigor Champions Prize winners! This $50K prize challenge sought to recognize individuals and small teams who are enhancing rigor and transparency. The goals were to: identify individuals or small teams of rigor champions who promote enhanced research rigor and transparency practices (beyond their normal job duties relevant to the neuroscience community and the biomedical community at-large); recognize and reward these rigor champions for these efforts; and raise awareness of these efforts more broadly. Read more about the winners at: https://lnkd.in/erusReNN Learn more about this prize challenge at: https://lnkd.in/eUM5Xiuk #NeurologicalDisorders #RigorChampions #Research #PrizeChallenges #PrizeCompetitions #PrizeWinners #WinPrizes The National Institutes of Health

𝐓𝐫𝐚𝐮𝐦𝐚𝐭𝐢𝐜 𝐁𝐫𝐚𝐢𝐧 𝐈𝐧𝐣𝐮𝐫𝐲 𝐚𝐧𝐝 𝐕𝐢𝐬𝐮𝐚𝐥 𝐏𝐫𝐨𝐜𝐞𝐬𝐬𝐢𝐧𝐠: 𝐄𝐱𝐩𝐥𝐨𝐫𝐢𝐧𝐠 𝐭𝐡𝐞 𝐂𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐨𝐧 𝐭𝐡𝐫𝐨𝐮𝐠𝐡 𝐚 𝐂𝐚𝐬𝐞 𝐒𝐭𝐮𝐝𝐲 Author: Leighton J Reynolds Abstract This article explores the often-unrecognized connection between a traumatic brain injury and problems with visual processing. It is increasingly being recognized that traumatic brain injuries are not limited to short-term neurological damage, but create long-term, neurodegenerative problems affecting many other systems in the body. These systems include cognitive, psychiatric and cardio-vascular issues. What is often left out is the effect traumatic brain injuries have on visual processing systems in the brain. This connection is explored through the case study of patient JM. In addition, concludes that while neuro-optometry has pioneered many useful techniques for restoring visual processing difficulties, if important structures in the brain have not healed then the brain is not capable of supporting all the processes that make up visual processing. An important key to making this happen is repairing the damage done to the mitochondria, the small but powerful Energy factories in nerve cells. 𝐓𝐨 𝐑𝐞𝐚𝐝 𝐅𝐮𝐥𝐥 𝐀𝐫𝐭𝐢𝐜𝐥𝐞: https://lnkd.in/gM9j7pYf #trauma | #optometry | #dementia | #parkinsons

Did you know that neurological disorders like Alzheimer's, Parkinson's, and epilepsy affect millions worldwide? 🧠 In my latest article, I delve into the complexities of these conditions, explore recent breakthroughs in research, and discuss potential treatment options. Curious to learn more about how these disorders impact brain function and what advancements are being made in the field? Click below to READ MORE and join the conversation! 💡 https://lnkd.in/eVwz4whC