Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking Associate Scientist/Scientist, Bioanalytical Sciences as part of the Early-Stage Drug Development team based in Somerset, NJ.
Role Overview
Legend Biotech USA, Inc. is seeking entry-level Scientists to join our Bioanalytical Sciences team responsible for daily Flow cytometry workflow to support immunophenotyping and cell-based assays of clinical samples. This position will report directly to the Senior Director of Bioanalytical Sciences. The successful candidates will perform 41 color panel flow assay using Cytek Aurora Spectral Flow cytometry for clinical samples autologous and allogenic CAR-T and related products. There will be plenty of opportunities to perform exploratory studies utilizing other analytical platforms such as molecular, immuno- and cell-based assays. The candidate will also collaborate with internal and external partners to ensure that the execution and analysis of clinical sample testing meets health authority guidelines and global qualification standards.
Key Responsibilities
Receive clinical trial specimens according to laboratory protocols via LIMS or paper-based process
Process patient samples and various quality control specimens for immunophenotyping and FACS
Maintain good documentation in ELN, paper notebook and log books.
Analyze flow cytometry data with SpectroFlow software
Conduct data transfer and storage according to department policies.
Keep work place clean and organized and adhere to EHS guidance.
Participate in assay development and qualification
Carry out additional exploratory and investigational studies with various analytical techniques.
Coordinate equipment maintenance, perform routine QC check and ensure proper working condition
Work with the various vendors in order to troubleshoot instrumentation issues
Maintain proper inventory of reagents, controls and disposables
Meet/exceed quality guidelines as they relate to performance, documentation and compliance
Perform other related duties as required
Requirements
Bachelor's or Master degree in biological sciences (Biology, Chemistry, Life Sciences) or related area is required
Knowledge of cancer biology, and immunology and T-cell biology.
> 2 years’ experience in execution of cell-based and /or flow cytometry methods preferred.
Prior experience in CAR-T cell therapy development preferred.
Knowledge of Spectral flow cytometers and hands on human PBMC preparation preferred
Strong critical thinking and problem-solving skills
Sense of ownership and integrity of their work.
This position requires to receive and analyze patient samples during off business hours occasionally.
A demonstrated ability to work as part of a team
Demonstrated organizational skills; including but not limited to attention to detail and multitasking
Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
Legend Biotech maintains a drug-free workplace.
Benefits:
Health Insurance
Dental Insurance
Vision Insurance
Life Insurance
Matched 401K
Flexible Spending Account
Health Savings Account
AD&D Insurance
Short-Term Disability
Long-Term Disability
Paid Maternity Leave
Paid Paternity Leave
Pet Insurance
Critical Illness Insurance
Hospital Indemnity Insurance
Accident Insurance
Legal Insurance
Commuter Benefits
Employee Assistance Program
Seniority level
Entry level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
Industries
Biotechnology Research
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