Cho Lab - Junior or Assistant Specialist
Cho Lab - Junior or Assistant Specialist
University of California, San Francisco
San Francisco, CA
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Position Description
A research specialist opportunity is available at the University of California, San Francisco in the Cho laboratory (cholab.ucsf.edu). The Cho lab is part of the UCSF Department of Radiation Oncology, the Department of Otolaryngology-Head and Neck Surgery, the UCSF Helen Diller Family Comprehensive Cancer Center, and the Parker Institute for Cancer Immunotherapy.
In the Cho Lab, we are focused on understanding the rules of engagement between cancer and the immune system. We aim to leverage fundamental, mechanistic discoveries to advance the treatment of cancer patients. Despite recent breakthroughs in cancer immunotherapeutics, there remains a significant knowledge gap particularly with respect to how interactions between cancer cells and immune cells determine treatment response vs. resistance. Our work using novel mouse and human models combined with high parameter immune profiling reveal critical molecular and cellular circuits responsible for resistance to immune checkpoint inhibitors and radiation therapy, including a surprising role for T cells in exacerbating immune-suppressive inflammation engaging immune and malignant cells in the tumor microenvironment. We aim to leverage expertise in molecular engineering and high parameter, single-cell profiling to understand key interactions at the tumor-immune interface to improve and innovate immune-based cancer therapy.
The Major Aims Of Our Research Program Are
The specialist will also be encouraged to take advantage of other training and learning opportunities within the UCSF Helen Diller Family Comprehensive Cancer Center, the UCSF ImmunoX Program, the Parker Institute for Cancer Immunotherapy, and other related entities at UCSF. We hope this experience will prepare the applicant for future opportunities in science.
Required Qualifications
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$65,900.
Document Requirements
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
San Francisco, CA
A research specialist opportunity is available at the University of California, San Francisco in the Cho laboratory (cholab.ucsf.edu). The Cho lab is part of the UCSF Department of Radiation Oncology, the Department of Otolaryngology-Head and Neck Surgery, the UCSF Helen Diller Family Comprehensive Cancer Center, and the Parker Institute for Cancer Immunotherapy.
In the Cho Lab, we are focused on understanding the rules of engagement between cancer and the immune system. We aim to leverage fundamental, mechanistic discoveries to advance the treatment of cancer patients. Despite recent breakthroughs in cancer immunotherapeutics, there remains a significant knowledge gap particularly with respect to how interactions between cancer cells and immune cells determine treatment response vs. resistance. Our work using novel mouse and human models combined with high parameter immune profiling reveal critical molecular and cellular circuits responsible for resistance to immune checkpoint inhibitors and radiation therapy, including a surprising role for T cells in exacerbating immune-suppressive inflammation engaging immune and malignant cells in the tumor microenvironment. We aim to leverage expertise in molecular engineering and high parameter, single-cell profiling to understand key interactions at the tumor-immune interface to improve and innovate immune-based cancer therapy.
The Major Aims Of Our Research Program Are
- To leverage high-parameter imaging and single cell proteomics to interrogate multicellular interactions in response to immune checkpoint inhibitors
- To interrogate consequences of stereotactic radiation on inflammatory T cell-tumor interactions
- To develop novel molecular and genetic tools to dissect cell-cell and cell-ligand interactions in the tumor microenvironment
The specialist will also be encouraged to take advantage of other training and learning opportunities within the UCSF Helen Diller Family Comprehensive Cancer Center, the UCSF ImmunoX Program, the Parker Institute for Cancer Immunotherapy, and other related entities at UCSF. We hope this experience will prepare the applicant for future opportunities in science.
Required Qualifications
- B.A. or B.S. (or equivalent) in biology, immunology, biochemistry, biomedical sciences, bioinformatics, computer science, chemistry, or a related scientific discipline (by time of hire)
- Strong self-motivation for curiosity-driven scientific research and study
- Flexibility and ability to work in a multidisciplinary team setting
- Strong problem-solving skills
- Strong communication and writing skills
- Programming skills, with a preference for experience in R and Python
- Prior research experience in cancer immunology
See Table 24B for the salary range for this position. A reasonable estimate for this position is $51,300-$65,900.
Document Requirements
- Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
- Cover Letter
- Statement of Research (Optional)
- Statement of Teaching (Optional)
- Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity Statement (Optional)
- Misc / Additional (Optional)
- 2-4 required (contact information only)
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
San Francisco, CA
-
Seniority level
Entry level -
Employment type
Full-time -
Job function
Research, Analyst, and Information Technology -
Industries
Higher Education
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