Biologist (Mice/Malaria)
Biologist (Mice/Malaria)
GAP Solutions, Inc.
Bethesda, MD
See who GAP Solutions, Inc. has hired for this role
Position Objective: Provide services as a Biologist (Mice/Malaria) in support of the overall functions of the Vaccine Research Center (VRC) within the National Institute of Allergy and Infectious Diseases (NIAID).
Duties and Responsibilities:
- Manage the execution of in vivo rodent research within the Malaria Insectary Facility.
- Perform a variety of procedures and techniques including (but not limited to) Plasmodium sporozoite dissection, in vitro functional assays, molecular cloning, PCR, cell culture, recombinant protein production, and multi-parameter flow cytometry.
- Expand and maintain mosquito cultures according to established protocols.
- Monitor the infection status of mosquitoes: blood feeding, natural transmission, and parasite isolations.
- Maintain malaria infected mosquito colonies and conduct in vivo malaria challenge experiments in rodents.
- Conduct pre-clinical evaluation (PK and PD experiments) for malaria vaccines and monoclonal antibodies in animal models.
- Develop methods to evaluate the protective effect of vaccines and mAbs in malaria in vivo models (via bioluminescence, immune- and clinical pathology analysis.
- Design rodent malaria layouts/challenges to establish new protocols, procedures, doses and risks for malaria experiments with the objective of providing data sets that support safe human testing.
- Proficiently perform common and specialized in vivo technical procedures necessary to maintain the progress of in vivo malaria experiments.
- Plan, execute, and arrange relevant experiments, techniques and procedures within appropriate quality standards and timelines.
- Regularly participate in meetings that are conducted to define vaccine development, antibodies, and manuscript publications on the area of malaria.
- Meticulously collect, analyze, interpret, and report data for presentations, reports, and publications from diverse malaria experiments.
- Record all procedures and research project data, data analyses, and analytical conclusions of analyses in government-authorized notebooks and electronic systems in accordance with applicable regulations and procedures.
- Monitor and maintain inventory of routine laboratory supplies to ensure maximum efficiency; make recommendations and prepare purchase requests as needed.
- Perform routine maintenance of the lab work area and specialized instruments and equipment.
Basic Qualifications:
- Bachelor’s degree in a related field.
- Minimum of four (4) years of related work experience.
- Requires extensive experience with relevant laboratory practices, materials, and practice.
- Must have hands on proficiency with common in vivo technical procedures in mice (compound administration, sample collection, imaging, surgery).
- Must have basic skills in applicable computer programs.
Minimum Qualifications:
- Preferred experience in the following techniques is highly desirable: preclinical malaria mouse challenge models, mosquito salivary gland/midgut dissection, IVIS in vivo imaging, multi- parameter flow cytometry, fluorescence microscopy, antibody/protein purification and characterization, ELISA, ELISPOT.
- Must strictly adhere to safety standards and lab policies and maintain compliance with necessary training.
- Must be able to work well both independently and with others on a team.
- Must be able to maintain high level of organization, accuracy and attention to detail.
- Must be able to make detailed observations, analyze data, and interpret results independently.
- Must be able to apply creative problem-solving skills and sound judgment in making timely decisions.
- Requires flexibility to handle multiple tasks and provide support for multiple projects in a fast- paced laboratory environment.
- Ability to communicate effectively, orally and in writing, with non-technical and technical staff.
- Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects
-
Seniority level
Associate -
Employment type
Full-time -
Job function
Research and Science -
Industries
Government Administration
Referrals increase your chances of interviewing at GAP Solutions, Inc. by 2x
See who you knowGet notified about new Biologist jobs in Bethesda, MD.
Sign in to create job alertSimilar jobs
People also viewed
-
Biologist 0 3 years
Biologist 0 3 years
-
Biologist
Biologist
-
Molecular Biologist
Molecular Biologist
-
As-Needed Biologist
As-Needed Biologist
-
Biology Scientist
Biology Scientist
-
Medical Laboratory Scientist / Medical Laboratory Technician
Medical Laboratory Scientist / Medical Laboratory Technician
-
Biologist
Biologist
-
Biologist
Biologist
-
Biology Scientist
Biology Scientist
-
Lab Scientist
Lab Scientist
Looking for a job?
Visit the Career Advice Hub to see tips on interviewing and resume writing.
View Career Advice Hub