Jim Koers

Indianapolis, Indiana, United States Contact Info
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About

Specialties: Drug Discovery, Drug Development, Project Management, CMC Project…

Activity

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Experience & Education

  • Eli Lilly and Company

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Volunteer Experience

  • Board of Directors

    Archdioces of Indianapolis CYO

    - 6 years 10 months

    Children

    Member of the Board of Directors for the Archdioces of Indianapolis CYO. Serving thousands of children in the central Indiana region. President of Board 2019

  • Board of Directors

    Camp Rancho Framasa

    - 6 years 10 months

    Children

    New member of the Board of Directors for Camp Rancho Framasa a United Way agency serving children from Central Indiana.
    www.campranchoframasa.org

  • Youth coach

    St. Simon The Apostle School

    - Present 15 years 7 months

    Children

    I have coached football, basketball, wrestling and lacrosse.

Publications

  • Apparatus and Initial Results for Pressurized Planar Electrochromatography

    Analytical Chemistry

    Pressurized planar electrochromatography (PPEC) is a new planar chromatographic technique in which the mobile phase is driven by electroosmotic flow, while the sorbent layer is pressurized in a manner that allows heat to flow from the layer through an electrically insulating, thermally conducting, sheet of aluminum nitride ceramic. A prototype apparatus for performing PPEC is described. Separation by PPEC is faster than by conventional TLC, and an example is presented of a 24-fold enhancement…

    Pressurized planar electrochromatography (PPEC) is a new planar chromatographic technique in which the mobile phase is driven by electroosmotic flow, while the sorbent layer is pressurized in a manner that allows heat to flow from the layer through an electrically insulating, thermally conducting, sheet of aluminum nitride ceramic. A prototype apparatus for performing PPEC is described. Separation by PPEC is faster than by conventional TLC, and an example is presented of a 24-fold enhancement in the speed of separation. PPEC was performed on both regular and high-performance C18 layers, and the latter yield substantially faster separation. The sorbent layer requires conditioning at elevated temperature before use, and solute migration velocity increases with this temperature. The flow rate increases in a linear manner with increasing voltage and diminishes in a nonlinear manner with increasing pressure. Both electrical current and Joule heating diminish with increasing pressure, and the diminution of flow at high pressure can be compensated by an increase in voltage. PPEC is more efficient than classical TLC. Theoretical plate heights diminish with increasing Rf and are in the range 29−21 and 55−27 μm for the high-performance and regular plates, respectively. PPEC retains the advantages of classical TLC but has the ability to separate a substantially higher number of samples simultaneously. An example is presented on the separation of nine samples in 1 min on a 2.5 cm × 10 cm sorbent layer.

    See publication

Patents

  • Method and apparatus for performing planar chromatography at elevated pressure

    Issued US 7,736,517

    According to one aspect of the disclosure, there is provided an apparatus (210) for performing electrochromatography. The apparatus (210) includes a die block (222) which is movable to exert a pressure greater than atmospheric pressure on a chromatography sample plate during performance of an electrochromatography procedure. A method of performing electrochromatography is also disclosed.

    See patent

Languages

  • English

    Native or bilingual proficiency

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