David Fajgenbaum, MD, MBA, MSc

Philadelphia, Pennsylvania, United States Contact Info
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David Fajgenbaum, MD, MBA, MSc, is a physician-scientist at the University of…

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Experience & Education

  • University of Pennsylvania School of Medicine

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Publications

  • Cytokine Storm

    New England Journal of Medicine

  • Chasing My Cure: A Doctor's Race To Turn Hope Into Action

    Ballantine/Penguin Random House

    The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure—and became a champion for a new approach to medical research.

    David Fajgenbaum was a former Georgetown quarterback nicknamed the Beast, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites…

    The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure—and became a champion for a new approach to medical research.

    David Fajgenbaum was a former Georgetown quarterback nicknamed the Beast, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for the equivalent of a game day overtime: a second chance.

    Miraculously, Fajgenbaum survived—only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. In parallel, he came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.

    More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment that he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.

    See publication
  • We Get It: Voices of Grieving College Students & Young Adults

    Jessica Kingsley Publishers

    Servaty-Seib & Fajgenbaum recently co-authored a book for grieving college students and young adults (Jessica Kingsley Publishers). A unique collection of 33 narratives by bereaved students and young adults, this books aims to help young adults who are grieving and provide guidance for those who seek to support them.

    Other authors
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Honors & Awards

  • Excellence in Research and Patient Advocacy Award

    National Disease Research Interchange

  • Atlas Award

    World Affairs Council of Philadelphia

    Received the 2016 Atlas Award along with then Vice President Joe Biden

  • 30 Under 30

    Forbes Magazine

    Healthcare category

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