Daniel Gartenberg PhD

Study objectives: Multisensor wearable consumer devices allowing the collection of multiple data sources, such as heart rate and motion, for the evaluation of sleep in the home environment, are increasingly ubiquitous. However, the validity of such devices for sleep assessment has not been directly compared to alternatives such as wrist actigraphy or polysomnography (PSG).

Purpose: In non-rapid eye movement (NREM) stage 3 sleep (N3), phase-locked pink noise auditory stimulation can amplify slow oscillatory activity (0.5– 1 Hz). Open-loop pink noise auditory stimulation can amplify slow oscillatory and delta frequency activity (0.5– 4 Hz). We assessed the ability of pink noise and other sounds to elicit delta power, slow oscillatory power, and N3 sleep. Participants and Methods: Participants (n = 8) underwent four consecutive inpatient nights in a… Show more

Purpose: In non-rapid eye movement (NREM) stage 3 sleep (N3), phase-locked pink noise auditory stimulation can amplify slow oscillatory activity (0.5– 1 Hz). Open-loop pink noise auditory stimulation can amplify slow oscillatory and delta frequency activity (0.5– 4 Hz). We assessed the ability of pink noise and other sounds to elicit delta power, slow oscillatory power, and N3 sleep. Participants and Methods: Participants (n = 8) underwent four consecutive inpatient nights in a within-participants design, starting with a habituation night. A registered polysomnographic technologist live-scored sleep stage and administered stimuli on randomized counterbalanced Enhancing and Disruptive nights, with a preceding Habituation night (night 1) and an intervening Sham night (night 3). Results: Total sleep time did not differ between conditions. Percentage of N3 was higher in the Enhancing condition, and lower in the Disruptive condition, versus Sham. Standard 0.8 Hz pink noise elicited low-frequency power more effectively than other pink noise, but was not the most effective stimulus. Both pink noise on the “Enhancing” night and sounds intended to Disrupt sleep administered on the “Disruptive” night increased momentary delta and slow-wave activity (ie, during stimulation versus the immediate pre-stimulation period). Disruptive auditory stimulation degraded sleep with frequent arousals and increased next-day vigilance lapses versus Sham despite preserved sleep duration and momentary increases in delta and slow-wave activity. Conclusion: These findings emphasize sound features of interest in ecologically valid, translational auditory intervention to increase restorative sleep. Preserving sleep continuity should be a primary consideration if auditory stimulation is used to enhance slow-wave activity. Show less

We developed and validated a new task that is the most sensitive measure of human alertness

We developed a way to detect errors in real-time on a supervisory control task using eye tracking.

We developed an app that addresses air travel anxiety based on UX techniques.

We identified the cognitive processes involved in reacquiring situation awareness using an eye tracker.

Adaptive automation (AA) can improve performance while addressing the problems associated with a fully automated system. The best way to invoke AA is unclear, but two ways include critical events and the operator's state. A hybrid model of AA invocation, the dynamic model of operator overload (DMOO), that takes into account critical events and the operator's state was recently shown to improve performance. The DMOO initiates AA using critical events and attention allocation, informed by eye… Show more

Adaptive automation (AA) can improve performance while addressing the problems associated with a fully automated system. The best way to invoke AA is unclear, but two ways include critical events and the operator's state. A hybrid model of AA invocation, the dynamic model of operator overload (DMOO), that takes into account critical events and the operator's state was recently shown to improve performance. The DMOO initiates AA using critical events and attention allocation, informed by eye movements. We compared the DMOO with an inaccurate automation invocation system and a system that invoked AA based only on critical events. Fewer errors were made with DMOO than with the inaccurate system. In the critical event condition, where automation was invoked at an earlier point in time, there were more memory and planning errors, while for the DMOO condition, which invocated automation at a later point in time, there were more perceptual errors. These findings provide a framework for reducing specific types of errors through different automation invocation. Show less

We investigated how to make mHealth technology that people will actually use.

An artificial intelligence model of human performance degradation in sustained attention tasks building towards a predictive model of the vigilance decrement.

Aging populations are at increased risk of sleep deficiencies (e.g., insomnia) that are associated with a variety of chronic health risks, including Alzheimer's disease and related dementias (ADRD). Insomnia medications carry additional risk, including increased drowsiness and falls, as well as polypharmacy risks. The recommended first-line treatment for insomnia is cognitive behavioral therapy for insomnia (CBTi), but access is limited. Telehealth is one way to increase access, particularly… Show more

Aging populations are at increased risk of sleep deficiencies (e.g., insomnia) that are associated with a variety of chronic health risks, including Alzheimer's disease and related dementias (ADRD). Insomnia medications carry additional risk, including increased drowsiness and falls, as well as polypharmacy risks. The recommended first-line treatment for insomnia is cognitive behavioral therapy for insomnia (CBTi), but access is limited. Telehealth is one way to increase access, particularly for older adults, but to date telehealth has been typically limited to simple videoconferencing portals. While these portals have been shown to be non-inferior to in-person treatment, it is plausible that telehealth could be significantly improved. This work describes a protocol designed to evaluate whether a clinician-patient dashboard inclusive of several user-friendly features (e.g., patterns of sleep data from ambulatory devices, guided relaxation resources, and reminders to complete in-home CBTi practice) could improve CBTi outcomes for middle- to older-aged adults (N = 100). Participants were randomly assigned to one of three telehealth interventions delivered through 6-weekly sessions: (1) CBTi augmented with a clinician-patient dashboard, smartphone application, and integrated smart devices; (2) standard CBTi (i.e., active comparator); or (3) sleep hygiene education (i.e., active control). All participants were assessed at screening, pre-study evaluation, baseline, throughout treatment, and at 1-week post-treatment. The primary outcome is the Insomnia Severity Index. Secondary and exploratory outcomes span sleep diary, actiwatch and Apple watch assessed sleep parameters (e.g., efficiency, duration, timing, variability), psychosocial correlates (e.g., fatigue, depression, stress), cognitive performance, treatment adherence, and neurodegenerative and systemic inflammatory biomarkers. Show less

Raising important methodological issues with research on the vigilance decrement.