“Jen was a pivotal & impactful leader of the Primary Care Pod, working across various Directors of Service Line Operations, National Primary Care Medical Directors, and functional teams to drive strategy and growth at Carbon. She ran highly effective biweekly meetings on primary care KPIs and strategic initiatives with the COO, CSO, CMO, VPs, and other executive leadership. Her leadership rallied the cross functional Team on Quality Metrics & related initiatives that positively impacted Carbon's patient outcomes. Jen impressively collaborated with product and data science to identify impactful opportunities for prioritization & roadmapping, such as new vs. established patient logic and correlation between orphan slot prevalence and utilization. She was a highly adept & motivating thought leader/partner in exploring as well as building out value-based care capabilities and vetting strategic contracts and partnerships. In summary, I would highly recommend Jen - she would be an instrumental addition to any team! I would love to work with Jen again in a heartbeat if given the opportunity!”
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President Biden's Executive Order on AI is out: https://lnkd.in/ew9xZfiP It requires more transparency in foundational models' red-team safety…
President Biden's Executive Order on AI is out: https://lnkd.in/ew9xZfiP It requires more transparency in foundational models' red-team safety…
Shared by Autumn Zhu
Experience & Education
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Odyssey
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Publications
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Imaging Glioma Initiation In Vivo Through a Polished and Reinforced Thin-skull Cranial Window
Journal of Visualizing Experiments
Glioma is the one of the most lethal forms of human cancer. Glioma relapse following radiation therapy is thought to arise from resistance of glioma stem cells (GSCs) to therapy. In vivo, GSCs are shown to reside in a perivascular niche that is important for maintaining their stem cell-like characteristics. Central to the organization of the GSC niche are vascular endothelial cells. Existing evidence suggests that GSCs and their interaction with the vascular endothelial cells are important for…
Glioma is the one of the most lethal forms of human cancer. Glioma relapse following radiation therapy is thought to arise from resistance of glioma stem cells (GSCs) to therapy. In vivo, GSCs are shown to reside in a perivascular niche that is important for maintaining their stem cell-like characteristics. Central to the organization of the GSC niche are vascular endothelial cells. Existing evidence suggests that GSCs and their interaction with the vascular endothelial cells are important for tumor development, and identify GSCs and their interaction with endothelial cells as important therapeutic targets for glioma. The presence of GSCs is determined experimentally by their capability to initiate new tumors upon orthotopic transplantation. This is typically achieved by injecting a specific number of GBM cells isolated from human tumors into the brains of severely immuno-deficient mice, or of mouse GBM cells into the brains of congenic host mice. Assays for tumor growth are then performed following sufficient time to allow GSCs among the injected GBM cells to give rise to new tumors-typically several weeks or months. Hence, existing assays do not allow examination of the important pathological process of tumor initiation from single GSCs in vivo. Consequently, essential insights into the specific roles of GSCs and their interaction with the vascular endothelial cells in the early stages of tumor initiation are lacking. Such insights are critical for developing novel therapeutic strategies for glioma, and will have great implications for preventing glioma relapse in patients. Here we have adapted the PoRTS cranial window procedure 16and in vivo two-photon microscopy to allow visualization of tumor initiation from injected GBM cells in the brain of a live mouse. Our technique will pave the way for future efforts to elucidate the key signaling mechanisms between GSCs and vascular endothelial cells during glioma initiation.
Other authors -
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Learning from Leaders in a Fast-Growing Field: Results of the First Dalberg Survey of Social Enterprise
Dalberg Global Development Advisors
Honors & Awards
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Forbes 30 Under 30
Forbes
https://www.forbes.com/profile/jen-zhu/#511859997d53
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HHS Execution of Major Projects Award
Center for Medicare and Medicaid Services
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CMS Innovation Center Employee of the Month
Center for Medicare and Medicaid Innovation
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Special Achievement Award
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Recognition of a special accomplishment of remarkable dedication, productivity and significance to the federal government.
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Time-Off Award
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Granted for noteworthy accomplishments or personal effort that contributes to the quality, efficiency or effectiveness of CMS operations.
Organizations
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Harvard Class Committee
Class President, First Marshal
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Harvard Undergraduate Council
Student Body Vice President
-•Elected only female of 12 freshman representatives in a race of 100+ candidates, first all-female ticket to win student body presidential elections since 2009. Spearheaded campus gender parity initiatives that led to all-time gender parity high of 49% on the Council. •Successfully advocated for creation of socially responsible choice fund by Harvard Management Company and working group to reexamine Harvard’s sexual assault resources and practices. Presented student issues to Board of Overseers…
•Elected only female of 12 freshman representatives in a race of 100+ candidates, first all-female ticket to win student body presidential elections since 2009. Spearheaded campus gender parity initiatives that led to all-time gender parity high of 49% on the Council. •Successfully advocated for creation of socially responsible choice fund by Harvard Management Company and working group to reexamine Harvard’s sexual assault resources and practices. Presented student issues to Board of Overseers at annual meeting. •Co-authored briefing on Harvard’s gun regulations and perceptions for the Office of the U.S. Vice President, memos on email privacy at Harvard and emergency communications in response to the 2013 Boston Marathon bombing and manhunt, and Case for a Harvard Student Center report used by Harvard President used to secure donor needed to build campus student center. •Created Annual Report to increase institutional memory, transparency, and accountability.
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