Vast Therapeutics

Vast Therapeutics

Biotechnology Research

Durham, NC 967 followers

Leveraging our proprietary nitric oxide technology to preserve lung function.

About us

Vast is a preclinical airway immunology company focused on breaking the vicious cycle of infection and chronic inflammation in respiratory diseases. The Vast technology platform begins with the unmatched antimicrobial activity of nitric oxide in the form of stable prodrugs. When our new chemical entities are combined with inhalation formulation expertise and proprietary chemistry for delivering drug candidates to the lungs, the result is aerosolized therapies targeting the specific needs of individual patient populations. Nitric oxide is an endogenous molecule that plays a vital role in the natural immune system response to microbial pathogens. Taking cues from human physiology, our nitric oxide based “antibiotic alternative” compounds are not susceptible to antimicrobial resistance mechanisms common to traditional antibiotics.

Website
http://www.vasttherapeutics.com
Industry
Biotechnology Research
Company size
11-50 employees
Headquarters
Durham, NC
Type
Privately Held
Founded
2017
Specialties
Pharmaceuticals, Biotech, and Therapeutics

Locations

Employees at Vast Therapeutics

Updates

  • Vast Therapeutics reposted this

    View organization page for Vast Therapeutics, graphic

    967 followers

    This week Founder and Chief Scientific Officer Mark Schoenfisch is at RDD 2024 and is presenting some exciting results from Vast Therapeutics' orally inhaled ALX1 development program for the treatment of chronic respiratory infections. Poster Title: Efficacy of Inhaled ALX1 in a Model of Chronic Pseudomonas Aeruginosa Infection Session: 2 - From Bench to Bedside (P8) Location: Arizona Ballroom “Treating respiratory infections safely and effectively remains a significant hurdle,” stated Dr. Mark Schoenfisch, Chief Scientific Officer at Vast Therapeutics. “Our study suggests that a nitric oxide-releasing prodrug delivered in a nebulized format is achievable and superior to standard of care (Tobramycin), which is exciting because nitric oxide does not engender resistance and should result in a more favorable tolerability profile than conventional antibiotics.” To view the poster click here: https://lnkd.in/eCajn9GK

    • No alternative text description for this image
  • View organization page for Vast Therapeutics, graphic

    967 followers

    This week Founder and Chief Scientific Officer Mark Schoenfisch is at RDD 2024 and is presenting some exciting results from Vast Therapeutics' orally inhaled ALX1 development program for the treatment of chronic respiratory infections. Poster Title: Efficacy of Inhaled ALX1 in a Model of Chronic Pseudomonas Aeruginosa Infection Session: 2 - From Bench to Bedside (P8) Location: Arizona Ballroom “Treating respiratory infections safely and effectively remains a significant hurdle,” stated Dr. Mark Schoenfisch, Chief Scientific Officer at Vast Therapeutics. “Our study suggests that a nitric oxide-releasing prodrug delivered in a nebulized format is achievable and superior to standard of care (Tobramycin), which is exciting because nitric oxide does not engender resistance and should result in a more favorable tolerability profile than conventional antibiotics.” To view the poster click here: https://lnkd.in/eCajn9GK

    • No alternative text description for this image
  • View organization page for Vast Therapeutics, graphic

    967 followers

    Vast Therapeutics announces an upcoming presentation at the 2024 Respiratory Innovation Summit being held in San Diego May 17-18, 2024. Dr. Nathan Stasko, Chief Executive Officer of Vast, will deliver an oral presentation on how its lead candidate, ALX1, is positioned to reshape the treatment landscape for several patient populations chronically infected with Pseudomonas aeruginosa. 2024 RIS Showcase Presentation Details: Session Title: Showcase Two: COVID, Infectious Disease and Other Innovators Session Date and Time: Saturday, May 18 at 10:15 a.m. PT Location: Manchester Grand Hyatt San Diego More information on the ATS 2024 Respiratory Innovation Summit can be found at https://lnkd.in/dJEGTQ3U.

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  • View organization page for Vast Therapeutics, graphic

    967 followers

    Exciting news today published by Vast Founder and Chief Scientific Officer, Mark Schoenfisch. "The broad-spectrum activity of our drug candidate plus the ability to kill mycobacteria that have invaded immune cells without engendering antimicrobial resistance is unprecedented." As a company we look forward to accelerating this technology into the clinic in 2024, as NTM pulmonary disease is a growing public health concern without alternatives to maintenance antibiotics that continue to propagate global antibiotic resistance. #antibioticresistance #ntm #copd #cysticfibrosis

    Vast Therapeutics Announces Publication of Potential New Treatment for Non-tuberculosis Mycobacteria Infections

    Vast Therapeutics Announces Publication of Potential New Treatment for Non-tuberculosis Mycobacteria Infections

    prnewswire.com

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