Nanite

If you missed the news, we're thrilled to share that Nanite received a $1.8M grant from the Bill & Melinda Gates Foundation to develop AI-driven gene therapy for HIV. With this funding, Nanite will employ its SAYER platform to design and optimize polymeric delivery vehicles to deliver DNA-encoded therapeutics, thereby durably producing therapeutic antibodies in vivo. Success would represent a significant breakthrough in HIV management, particularly in populations with limited access to care.

Our recent cover art & work on "Predictive design of multimonomeric polyelectrolytes enables lung-specific gene delivery" is now #OpenAccess in the Royal Society of Chemistry journal Polymer Chemistry for a month! Reach out with any questions about our lung delivery capabilities (https://lnkd.in/gtwhM2ux). Please join us in congratulating the Nanite R&D team and sharing this work with your colleagues 👏 🧬 🧪 #genetherapy #biotech #techbio #machinelearning #AI https://lnkd.in/gdkhGzck

Congrats to the entire Nanite team (John Fisher, Ph.D. Tyler Conyers Suteja Patil Catherine Robohn Teresa Tamayo Felipe Oviedo Shashi Murthy) on our article “Predictive design of multimonomeric polyelectrolytes enables lung-specific gene delivery” — selected for the Royal Society of Chemistry journal Polymer Chemistry cover! 🧬🧪✨ A pointillism inspired representation of our data-driven approach to gene delivery -- big shoutout to Teresa for using the helping us apply a pointillism algorithm to the image: from thousands of individual data points, we can build together patterns that form fantastic new ideas and delivery vehicles 😁 Link to cover: https://lnkd.in/enRfDbDy Link to paper: https://lnkd.in/e9dmSMAk

Happy July! This week we are thrilled to welcome three bright and talented Northeastern University interns— Maeve Ryan, Olivia Heynes, & Zoe Apostolopoulos — to the Nanite biology and polymers teams! Join us in extending a warm welcome to our new interns! We’re excited to give them an enriching experience as they contribute to our mission of advancing non-viral gene therapy to new frontiers 📦🧬🧪🧫🙏🏻 #biotech #internship #welcometotheteam #genetherapy #machinelearning

Kicking off Friday with a 🆕 publication! 🎉 Congratulations to our Head of ML/AI, Felipe Oviedo, and the Reineke Lab at University of Minnesota on their new paper, "Synergistic Polymer Blending Informs Efficient Terpolymer Design and Machine Learning Discerns Performance Trends for pDNA Delivery" in American Chemical Society Bioconjugate Chemistry 🧬🧪🤖 👉🏻 https://lnkd.in/erYqVq4D ‣ Cationic polymers offer a powerful alternative to viral vectors in nucleic acid delivery. ‣ However, the development of polymer nanoparticles capable of high transfection efficiency and minimal toxicity has remained elusive, and continued exploration of a vast design space is required. ‣ Traditional single polymer syntheses with large monomer bases are very time-intensive, limiting the speed at which new formulations are identified. ‣ Read this paper to learn how this new workflow can expedite the exploration of polymer design spaces, bypass extensive synthesis, and develop data-driven polymer delivery vehicles more readily for nucleic acid therapies. #biotech #genetherapy #bioconjugatechemistry #machinelearning #AI

Join us in congratulating Shashi Murthy on being recognized for exceptional co-op mentorship and excellence in supervision 👏🏻

Last Friday we celebrated the conclusion of Catherine Robohn, Joshua McDonald, and Cassandra Vongrej’s time with us at Nanite by racing cars at the Seaport F1 Arcade 🏎️💨💨 Good luck finishing up your education in the fall— we’re excited to see all the amazing things you all will do in the future!!! 🚀

🎉 The Nanite Team Goes to Fenway! 🌟 Yesterday, our incredible R&D team at Nanite had an unforgettable summer outing at a Red Sox game! 🧢⚾🌭 It was a fantastic day filled with sunshine, camaraderie, and of course, cheering for our home team at Fenway Park. These moments remind us how important it is to take a break, have fun, and bond as a team outside of the lab. Our passion for scientific innovation and teamwork doesn’t just stay at work – this hallmark shines through in everything we do, on and off the field. 🌞🙌 A huge shoutout to Sue Connolly who helped organize this outing and to our team members for bringing their enthusiasm and spirit. We’ve accomplished so much the first half of 2024, and we’re excited to share more use-cases of how AI-driven polymer design is transforming delivery challenges soon. Here’s to more exciting adventures together! 🥳🚀 #TeamBuilding #SummerOuting #RedSoxGame #Nanite #GeneTherapy #AI