To investigate whether the transcriptional activator hypoxia-inducible factor 1 (HIF-1) is
required for ventilatory responses to hypoxia, we analyzed mice that were either wild type or …

Postnatal deficits in brain-derived neurotrophic factor (BDNF) are thought to contribute to
pathogenesis of Rett syndrome (RTT), a progressive neurodevelopmental disorder caused by …

The respiratory system is highly pliable in its adaptation to low-oxygen (hypoxic) environments.
After chronic intermittent hypoxia (CIH), alterations in the regulation of cardiorespiratory …

1 The role of endogenous nitric oxide (NO) generated by neuronal nitric oxide synthase (NOS‐1)
in the control of respiration during hypoxia and hypercapnia was assessed using …

10.1152/jn.00224.2002. Dopamine (DA) modulates the cardiorespiratory reflex by peripheral
and central mechanisms. The aim of this study was to examine the role of DA in synaptic …

Changes in the physiological state of an animal or human can result in alterations in the
cardiovascular and respiratory system in order to maintain homeostasis. Accordingly, the …

Peripheral chemoreceptor afferent information is sent to the nucleus tractus solitarii (nTS),
integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS …

Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are highly expressed in the
nucleus tractus solitarius (nTS), the principal target of cardiovascular primary afferent input …

The autonomic nervous and respiratory systems, as well as their coupling, adapt over a wide
range of conditions. Chronic intermittent hypoxia (CIH) is a model for recurrent apneas and …

Objective Kv1.1 potassium channel null mouse (NULL) exhibits spontaneous seizure‐related
bradycardia, dies following seizure, and has been proposed as a model for vagus‐…