User profiles for Arthur P. Arnold

Arthur P. Arnold

Distinguished Research Professor, UCLA Department of Integrative Biology & Physiology
Verified email at ucla.edu
Cited by 38428

The organizational–activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues

AP Arnold�- Hormones and behavior, 2009 - Elsevier
The 1959 publication of the paper by Phoenix et al. was a major turning point in the study of
sexual differentiation of the brain. That study showed that sex differences in behavior, and by …

[PDF][PDF] Gonadal steroid induction of structural sex differences in the central nervous system

AP Arnold, RA Gorski�- Annual review of neuroscience, 1984 - researchgate.net
In the last decade, we have experienced a small revolution in the study of the neural and
hormonal bases of sex differences in behavior and reproductive function. The previous view …

Reframing sexual differentiation of the brain

MM McCarthy, AP Arnold�- Nature neuroscience, 2011 - nature.com
In the twentieth century, the dominant model of sexual differentiation stated that genetic sex (XX
versus XY) causes differentiation of the gonads, which then secrete gonadal hormones …

A general theory of sexual differentiation

AP Arnold�- Journal of neuroscience research, 2017 - Wiley Online Library
A general theory of mammalian sexual differentiation is proposed. All biological sex differences
are the result of the inequality in effects of the sex chromosomes, which are the only …

Forebrain lesions disrupt development but not maintenance of song in passerine birds

SW Bottjer, EA Miesner, AP Arnold�- Science, 1984 - science.org
The magnocellular nucleus of the anterior neostriatum is a forebrain nucleus of passerine
birds that accumulates testosterone and makes monosynaptic connections with other …

Hormone accumulation in a sexually dimorphic motor nucleus of the rat spinal cord

SM Breedlove, AP Arnold�- Science, 1980 - science.org
The fifth and sixth lumbar segments of the rat spinal cord were found to contain a sexually
dimorphic nucleus, the spinal nucleus of the bulbocavernosus (SNB). The SNB, which …

Sex chromosomes and brain gender

AP Arnold�- Nature Reviews Neuroscience, 2004 - nature.com
In birds and mammals, differences in development between the sexes arise from the
differential actions of genes that are encoded on the sex chromosomes. These genes are …

What does the “four core genotypes” mouse model tell us about sex differences in the brain and other tissues?

AP Arnold, X Chen�- Frontiers in neuroendocrinology, 2009 - Elsevier
The “four core genotypes” (FCG) model comprises mice in which sex chromosome complement
(XX vs. XY) is unrelated to the animal’s gonadal sex. The four genotypes are XX gonadal …

Androgens regulate the dendritic length of mammalian motoneurons in adulthood

EM Kurz, DR Sengelaub, AP Arnold�- Science, 1986 - science.org
Sex steroid hormones have been thought to alter behaviors in adulthood by changing the
activity of neural circuits rather than by inducing major structural changes in these pathways. In …

Sexual dimorphism in vocal control areas of the songbird brain

F Nottebohm, AP Arnold�- Science, 1976 - science.org
In canaries and zebra finches, three vocal control areas in the brain are strikingly larger in
males than in females. A fourth, area X of the lobus parolfactorius, is well developed in males …