The book also reviews the structure of key nuclear receptor co-regulatory proteins.

This book is the first this century to try and capture the spirit of this endeavour, to depict where the field is now and to identify some of the challenges and opportunities for the future.

Receptors included in this book are: The Nuclear Receptor Superfamily Thyroid Hormone Receptors Estrogen and Progesterone Receptors The Androgen Receptor DAX-1 and Related Orphan Receptors The Vitamin D Receptor Retinoid Receptors ...

The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups.

Written in the highly successful Methods in Molecular BiologyTM series format, the chapters in this volume contain brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible ...

The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups.

mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance. Clinic. Endocrinol. 55(3) ... structure. J. Steroid Biochem. Molec. Biol. 68(3–4), 89–102. Savory, J. G., Prefontaine, G. G., Lamprecht, C�...

... structure . 21,33,43 This drug is currently being evaluated in the clinic as a second line intervention for patients with tamoxifen refrac- tory disease . The successful outcome of this project highlights the utility of mechanism�...

... clinic . Higher - throughput , less definitive methods ( e.g. , in silico ) and nuclear receptor - based assays are ... structure information of the nuclear receptor proteins with the in silico structural biology . For this�...

... receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther 2004 ... nuclear signaling by G proteincoupled receptors and their ligands. FASEB J 2007; 21: 638– 642. Moore CA, Milano SK�...