Teodora Figueiredo ^1,2,3 Luís Midão ^1,2,3 Joana Carrilho ^1,2,3 Diogo Videira Henriques ^1,2,3 Sara Alves ⁴ Natália Duarte ⁴ Maria J. Bessa ⁵ José M. Fidalgo ⁶ Maria García ⁶ David Facal ⁷ Alba Felpete-López ⁷ Iván R. Filgueira ⁸ Juan Carlos Bernárdez ⁸ Maxi Rodríguez ⁸ Elisio Costa ^1,2,3*

• ¹ CINTESIS@RISE, Biochemistry Lab of the Faculty of Pharmacy of the University of Porto, Porto, Portugal
• ² Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal
• ³ Competences Centre on Active and Healthy Ageing, Faculty of Pharmacy, University of Porto, Porto, Portugal
• ⁴ Santa Casa da Misericórdia de Riba D’Ave/CIDIFAD – Centro de Investigação, Diagnóstico, Formação e Acompanhamento das Demências,, Braga, Braga, Portugal
• ⁵ UPTEC - Science and Technology Park of University of Porto, Porto, Portugal
• ⁶ ACIS- Agencia Gallega para la Gestión del Conocimiento en Salud, Santiago de Compostela, Galicia, Spain
• ⁷ Department of Developmental Psychology. Faculty of Psychology, University of Santiago de Compostela, Santiago de Compostela, Spain
• ⁸ Association of Relatives of Patients with Alzheimer's and other Dementia of Galicia, Vigo, Spain

The increasing prevalence of dementia demands innovative solutions; however, existing technological products often lack tailored support for individuals living with this condition. The Living Lab approach, as a collaborative innovation method, holds promise in addressing this issue by actively involving end-users in the design and development of solutions adapted to their needs. Despite this potential, the approach still faces challenges due to its lack of recognition as a research methodology and its absence of tailored guidelines, particularly in dementia care, prompting inquiries into its effectiveness. This narrative review aims to fill this gap by identifying and analysing digital health Living Labs focusing on dementia solutions. Additionally, it proposes guidelines for enhancing their operations, ensuring sustainability, scalability, and greater impact on dementia care. Fifteen Living Labs were identified and analysed. Based on trends, best practices, and literature, the guidelines emphasise user engagement, interdisciplinary collaboration, technological infrastructure, regulatory compliance, transparent innovation processes, impact measurement, sustainability, scalability, dissemination, and financial management. Implementing these guidelines can enhance the effectiveness and long-term impact of Living Labs in dementia care, fostering new collaborations globally.