› 8ati

X-ray diffraction
2.6Å resolution

Human CtBP2(31-364) in complex with RAI2 peptide(315-322)

Released:
DOI: 10.2210/pdb8ati/pdb
PDB entry 8ati coloured by chain, front view.
PDB entry 8ati coloured by chain, side view.
PDB entry 8ati coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Mullapudi E, Goradia N, Wilmanns M

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-239694 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
C-terminal-binding protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 353 amino acids
Theoretical weight: 39.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P56545 (Residues: 31-364; Coverage: 75%)
Gene name: CTBP2
Sequence domains:
Retinoic acid-induced protein 2 Chains: a, b, c
Molecule details ›
Chains: a, b, c
Length: 243 amino acids
Theoretical weight: 25.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y5P3 (Residues: 303-465; Coverage: 31%)
Gene name: RAI2

Ligands and Environments

2 bound ligands:
Ligand NAD 4 x NAD
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P6122
Unit cell:
a: 126.646Å b: 126.646Å c: 357.598Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.228 0.283
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli

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