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Evolution and host-specific adaptation of Pseudomonas aeruginosa. Weimann A, Dinan AM et al. Science. 2024 Jul 5;385(6704):eadi0908.

Electric nuclear quadrupole coupling reveals dissociation of HCl with a few water molecules. Xie F, Tikhonov DS, Schnell M. Science. 2024 Jun 28;384(6703):1435-1440.

Structural insights into the cross-exon to cross-intron spliceosome switch. Zhang Z, Kumar V et al. Nature. 2024 Jun 27;630(8018):1012-1019.

Structural mechanism of angiogenin activation by the ribosome. Loveland AB, Koh CS et al. Nature. 2024 Jun 20;630(8017):769–776.

Kainate receptor channel opening and gating mechanism. Gangwar SP, Yelshanskaya MV et al. Nature. 2024 Jun 20;630(8017):762–768.

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June 17-18, 2024

Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable June 17-18 PDT.

October 30-31, 2023

Planned downtime: The Chimera and ChimeraX websites and associated web services will be unavailable Oct 30 8am PDT – Oct 31 11:59pm PDT.

April 19, 2023

Chimera production release 1.17.1 is now available, fixing an issue with 1.17 for Windows and Linux. See the release notes for details.

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Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

DNA and netropsin

Molecular Graphics

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Gallery Sample

Loop Interactions

The image shows interactions of the delta-1 loop with the rest of hepatitis C virus RNA-dependent RNA polymerase (Protein Data Bank entry 1quv). Loop residues in contact with the rest of the structure (van der Waals overlap ≥ 0.01 Å) are displayed as sticks; interacting surface atoms are shown as red patches. (More samples...)


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