��� We are thrilled to introduce our CMC consultant Dr Dima Al-hadithi Al-Hadithi from Minaret Consultancy. 🥼 Dima is solution-driven and fantastic to work with and brings a wealth of valuable skills to ikarovec to support the advancement of our manufacturing process and formulation development for our ophthalmic gene therapy products. 🧬 Dima is an experienced pharmaceutical & regulatory consultant with a broad range of experience working at an operational level from early development, product registration and post-approval life cycle management, with a strong skill set spanning regulatory, CMC and quality. #WelcomeAboard #Team #genetherapy #biotechstartup #AMD #ophthalmology #CMC #regulatory #advancedtherapies
ikarovec
Biotechnology Research
ikarovec is a UK-based biotech gene therapy company with a therapeutic focus in ophthalmology.
About us
The company has an early stage pipeline of novel, multi-cistronic gene therapy products targeting diabetic macular edema (DME), age-related macular degeneration (AMD, both wet and dry forms) and ocular hypertension.
- Website
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http://www.ikarovec.com
External link for ikarovec
- Industry
- Biotechnology Research
- Company size
- 2-10 employees
- Headquarters
- Norwich
- Type
- Privately Held
- Founded
- 2018
- Specialties
- gene therapy , ophthalmology, diabetic macular edema (DME), wet age-related macular degeneration, geographic atrophy, and ocular hypertension
Locations
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Primary
Innovation Centre
Norwich, NR4 7GJ, GB
Employees at ikarovec
Updates
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🎈 ikarovec have reached another important milestone… Our 4th Birthday! The company began operating out of Norwich in July 2020, and in that time we have progressed through the discovery and pre-clinical phases of our innovative gene therapies for geographic atrophy and wet-AMD. We can’t wait to see what the future brings! 🎉 #workanniversary #happybirthday #genetherapy #biotechstartup #AMD #ophthalmology
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Ikarovec is excited to be part of the Cell and Gene Therapy Catapult Consortium, partnering with Croda and UCL, to advance the development of formulation buffers for their lead AAV vector targeting GA. 🔍 💡 🔬
Today we announce the establishment of a new cross-industry consortium to improve the understanding and process optimisation of adeno-associated virus (AAV) formulation. The consortium comprises Croda, ikarovec , UCL's department of Biochemical Engineering, and the Cell and Gene Therapy Catapult (CGT Catapult). Initial scoping of the consortium was conducted by the CGT Catapult, which included interviews with key opinion leaders and a stakeholder workshop, revealing AAV formulation and stability characterisation as an important, underdeveloped area of unmet need. The project has received funding from Innovate UK, through its Transforming Medicines Manufacturing Programme Learn more: https://lnkd.in/dsk6TNtB #transformingmedicinesmanufacturing #advancedtherapies #AAV #genetherapy
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"ikarovec’s unique approach of combining two different proteins into a single vector has the potential to address many of the complex challenges associated with Geographic Atrophy." - Andrew Osborne, Ph.D., ikarovec’s Head of Biology. Excited to share recent ground-breaking findings in our gene therapy approach 👇 👉 Slowing down the activation of the complement cascade 👉 Protecting key retinal cells from damage 📍 And subsequently, the progression of Geographic Atrophy. We couldn’t be more proud of our team for all their hard work in helping us get to this point. #Investment #VentureCapital #GeneTherapy #FuturePlanetCapital
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Ikarovec’s CSO Katie Binley took part in the One Nucleus On Helix panel discussion today all about the Boston Bootcamp. It was a great opportunity for the panel to share learnings, challenges and opportunities from the experience with the Cambridge UK life sciences ecosystem.
The ON Helix session 'Translational Research in a Global Village' included a panel discussion on 'Learning from Boston Bootcamp,' with Ross McNaughton Taylor Wessing, Katie Binley, ikarovec Matthew Fyfe, STORM Therapeutics Limited, Mike Davies, MD, FRCS, Carocell Bio, Hazel Jones, ENHANC3D GENOMICS
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This week ikarovec CSO Katie Binley was thrilled to be selected to give a presentation at the British Society for Gene and Cell Therapy (BSGCT) in the CNS & Ocular session chaired by Carly Bliss & @Michelle McClements. It was a honour to speak alongside Simon Waddington (development of a much needed gene therapy to treat dopamine transporter deficiency , hDAT) Jasmina Cehajic Kapetanovic (clinical gene therapies for inherited retinal diseases including RPGR, optogenetics and robotic assisted surgery), @Ralph Hector (a self regulating gene therapy for Rett Syndrome) and @Katie Greed who gave a passionate and personal presentation of living with Phelon McDermid Syndrome (PMS)
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ikarovec have been busy closer to home this week. The Norwich team attended Enterprise Tuesday, hosted by the Norwich Research Park learning more about the wealth of technology platforms here at the research park. We also attended the Health Research and Innovation event on Wednesday, which was a great showcase of the research and innovation happening in the East of England. #enterprisetuesday #norwichenterprise #biotech #UEA #NorwichResearchPark #networking #healthUEA
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📣 Katie Binley, ikarovec’s Chief Scientific Officer, will give an oral presentation on Tuesday 18th June at the Annual British Society for Gene and Cell Therapy (BSGCT) in Oxford at the Saïd Business School, University of Oxford. The talk will focus on the exciting scientific achievements at ikarovec from the design of a next generation bicistronic AAV-based gene therapy to treat geographic atrophy through to the demonstration of robust efficacy in key proof-of-concept ocular models. #genetherapy #AMD #ophthalmology
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JUNE 2024: ikarovec strategy meeting at the Rooftop Gardens in Norwich with Andrew Osborne Emily Francesca Warner Laura Vaux and Katie Binley the sunshine ☀️ and cocktails 🍹 were very welcome ! #teambuilding #oculargenetherapy #planningforsuccess
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📣 ikarovec are proud to announce their partnership with the Cell and Gene Therapy Catapult, Croda, and UCL, supported by a grant from Innovate UK. 💡 This collaborative 2-year project will discover and test new formulations and analytical technologies for AAV gene therapies, including our ground-breaking treatment for Geographic Atrophy. 🧪 Formulation research is crucial for drug stability, potency, safety, and COGs. This project will enhance our therapy and provide valuable insights for the wider industry. ⭐ More updates to come. Thank you to Innovate UK for co-funding this partnership and CGT Catapult for leading the efforts, we look forward to working with all of our collaborative partners on this exciting and important project! #InnovateUK #transformingmedicinesmanufacturing #genetherapy #formulation #AMD #ophthalmology #successfulgrant #UKRI_News