Compiled by Pete Coulman

December 10, 1979

Coincident with the opening of a new bridge extending Islington Avenue over the CN railway tracks between Judson and New Toronto streets, a new bus route is established, extending bus service on Islington south from Judson to Lake Shore Boulevard. Buses on 110 ISLINGTON SOUTH operate from Islington station via east on Bloor and south on Islington to loop via west on Lake Shore, north on Eighth and east on Birmingham to Islington, returning via the reverse route. Buses operate Monday to Friday, during rush hours and midday. Service operates out of Queensway garage.

February 17, 1980

Weekday evening and weekend service added. Buses now run every ten minutes during rush hours, and every twenty minutes at all other times, seven days a week, 18 hours a day.

February 9, 1987

Night service on Islington Avenue established on the 311 ISLINGTON NIGHT bus.

September 3, 1989

Service absorbs the 38 HORNER route, “in order to provide a more blended service on Islington Avenue”.

Service on the 110 branch remains the same. Service on the original 38 branch designated 110A, operating from Islington station via south on Islington, west on Judson, west on Horner, south on Brown’s Line and west on Lake Shore to Long Branch loop, returning via the reverse route. Buses operate seven days a week, 18 hours a day.

Service on the old 38A branch designated 110B. Effective Tuesday, September 5, buses operate from Islington station via south on Islington, west on Judson, west on Horner, south on 30th Street and west on Lake Shore to Long Branch loop, returning via the reverse route. Buses on this branch operate during rush hours only.

All buses leave from the same bus bay at Islington station.

January 8, 1995

Southern looping at Lake Shore and Islington expanded. Buses operate via south on Islington, west on Lake Shore, north on 12th Street, east on Garnatt Janes Road, north on Ninth Street, east on Birmingham to Islington. No change to the destination signs (among the last remaining on the system).

February 18, 1996

As part of system-wide service cuts resulting from the elimination of provincial subsidy for public transit, service on the 110A “Horner-Brown’s Line” branch eliminated after 7:00 p.m. Saturdays and all day Sundays. On the 110 branch, Saturday evening and Sunday evening service reduced to every 30 minutes.

June 22, 2008

Accessible service launched.

November 23, 2008

As part of the TTC’s Ridership Growth Strategy, Saturday evening and all-day Sunday service reinstated on the 110A “Horner-Brown’s Line” branch. Buses operate at frequencies of 30 minutes or better whenever the subway is open.

August 2, 2009

Bike rack service launched.

June 22, 2014

As part of a system-wide restructuring of TTC route branch designations, southbound 110 “main” branch buses to Lake Shore and Islington are redesignated 110C.

March 26, 2023

Buses on the 110C “Lake Shore” branch are extended to Kipling Loop. Buses operate west on Lake Shore to Kiping Loop, and return east to 13th Street where it will pick up the current loop route via Garnett Janes, Ninth and Birmingham back to Islington.

110 Islington South Image Archive

	TTC Orion VII bus heads along the Brown's Line off-ramp towards Long Branch Loop in 110 ISLINGTON SOUTH service. This shot was taken by Edward Brain on June 12, 2021.
	An official TTC map of 110 ISLINGTON SOUTH operations, effective June 19, 2011.
	A scan of a TTC front rollsign showing the exposures for 110 ISLINGTON SOUTH. This photo, taken on September 2, 1990, is courtesy Joseph Chemerys at the Rollsign Gallery.
	TTC Flyer D-700 bus #7509 pulls into Islington subway station in service on 110 ISLINGTON SOUTH on April 2, 1986. Photo by Ted Wickson, from the John Knight collection.
	TTC Orion VII bus #7962 operates westbound on Lake Shore Boulevard between 8th and 9th Streets at the south end of the 110 ISLINGTON SOUTH route. This March 2016 shot was taken by Edward Brain.
	TTC Flyer D-800 bus #7989 pulls into Islington station in service on 110 ISLINGTON SOUTH. This August 1988 shot was donated by Pete Coulman. The photographer is unknown.
	TTC Orion V bus 8043 departs Islington station heading south to Long Branch. This photo was taken by Roman Fomin on December 14, 2011.
	TTC Orion VII bus #8094 picks up passengers at Long Branch loop, in service on 110 ISLINGTON SOUTH, "Brown's Line" branch, on May 23, 2015. Photo by John Marbella
	TTC GM T6H-5307 "New Look" bus #8653 departs Islington station in 110 ISLINGTON SOUTH service on August 20, 1982. The photograph is by T.E. Dorsey and is courtesy the Gilbert Ebling collection.
	TTC ALRV 4226 passes TTC prototype LRV 4401 at Long Branch loop on May 12, 2014, while TTC Orion VII bus 8036, in service on 110A ISLINGTON SOUTH, looks on. Photo by Edward Brain.