If anyone has read my reviews and/or answers on questions you will see that in the past year my family has gotten really into the Ticket To Ride (TTR) games. Well, while purchasing one of my latest TTR expansions I stumbled upon the Pandemic games; which are similar to the TTR ones in that you start with a base game, get the foundation for rules and game play and then you start moving on to expansions with additional features. I purchased Pandemic and with Amazon Prime it was delivered in less than 24 hours, no kidding! As is my usual custom I read the instruction manual and then because I am a visual learner I went to You Tube to watch some videos. ZManGamesOfficial does a 9.5 minute brief tutorial. WatchItPlayed does a wonderful job walking you through the game prep for a 2-player game including where all pieces, cards, etc. go. This was very helpful as there are specific instructions on how to shuffle and stack the Player Cards. My niece and I had this video up while setting up the first game. Finally, I watched Geek & Sundry do their TableTop version of the game where you actually get to see the players play. They have an abbreviated video and then a 1.5 hour extended game play. So, these are just tips that helped us get an understanding of the game play and we had a blast!Pandemic allows you to travel from the Center for Disease Control in Atlanta and you travel throughout the world trying to cure and eradicate 4 diseases. The instructions make it sound so easy but oh boy; it is not. Game play can be learned in about 15-30 minutes. The difficult part and it is not the actual game-play; is trying to come up with enough strategies fast enough to cure and eradicate the diseases before you and your team die! Yes, team...unlike TTR this is not a game 1 player wins. It's a collaborative game in which all players work together...you discuss how you can unite forces, share your special roles, your cards, etc. But be careful of an alpha player who may start bossing people around, telling them what to do and takes charge of the game. If you get an alpha player just let them have the game board, pawns, etc. and tell them to play the game by them self but as if they were many players. In the end if it's your turn you can listen to others, even the alpha player, but what you do is totally up to you. If you don't have a good strategy everyone loses...my niece and I call it dying because we have succumbed to the disease.So, why is it a race against the clock? Well, no matter how well your strategy, your team can "die" IF you: Have 8 outbreaks before curing/eradicating all 4 diseases, you run out of Disease Cubes or Player Cards. Note: You don't have to eradicate all 4 diseases to win; you just have to cure all 4. First game we cured all 4 diseases and eradicated the yellow ("Crazy Banana Disease") but we got 8 outbreaks...we saved the world! 2nd game; yes, we played another because we were feeling lucky! We cured all 4 diseases, didn't eradicate any and once again we saved the world. We named our diseases the Black Zombie Plague, Purple People Eater (Blue cubes), Angry Bird Virus (red) and of course the Crazy Banana Disease (yellow) because my niece named it while infecting Miami.During your turn you can play up to 4 actions, draw 2 Player Cards but you cannot be holding more than 7 at any given time and then you MUST infect cities! The Infection Rate starts at 2 cities per player, per turn. But every time a player draws an Epidemic Card they have to move the Infection Rate marker and it slowly increases the Infection Rate from 2 cities up to 4 cities. The Epidemic card also requires you to draw 1 city from the bottom of the Infection cards and you must infect that city with 3 disease cubes; 1 more cube of the same color and you have an outbreak, oh my! Finally, the Epidemic Card requires you to "intensify" the Infection Cards. That means you must shuffle all the Infection Cards (cities) that have been played since the last epidemic, including the city card you just drew from the Infection Card pile and then put them back on top of the Infection Card pile so they now go back into play. See the intensity? With just my niece and me playing we didn't have as many cards to reshuffle so we kept infecting the same cities; which in essence was then producing outbreaks faster. I "think" you may have a longer game play with more people because then the other players will also be contributing cards.An outbreak occurs if/when a city accumulates 4 of the same color disease cubes. When this happens you must put a disease cube of that same color in every city that is directly attached to the city that the outbreak occurred in, thus, the epidemic. Note: It's possible that you have infected a city with more than 1 disease so IF you have 4 or more disease cubes but they are different colors you do NOT have an outbreak. The outbreak is only when you get 4 of the same color in the same city but the 4th cube (same color) will not be placed on the city. So watch those disease cubes and treat and cure so you can prevent the outbreaks.Now when you play up to 4 actions during each turn you have an option to treat a disease. You treat by removing 1 or more disease cubes from the city you are in (each cube being an action) that you have used your actions and/or role to get to. I was the Medic during first game and one of my roles allowed me to remove ALL disease cubes from the city I was in or traveled to! The Dispatcher can move players from city to city with their permission so once again...If you have a Dispatcher in the same game with a Medic you can move the Medic to the city that needs to be treated and get rid of all the disease cubes. IF the disease has been cured (see above pic...the disease markers are solid colors and moved above the disease logos) then you get to remove ALL the disease cubes in that city EVEN IF you aren't the Medic. To eradicate the disease you must remove ALL disease cubes of the same color from every city on the board. When you have eradicated the disease you flip the disease marker over to reveal the little log for eradicated. Note: Cities can still be infected if the disease has been cured but NOT if it has been eradicated.Back to the outbreaks. There's also an outbreak chart with marker and each time an outbreak occurs you have to move the marker. If you have 8 outbreaks the game is over and there is no winner because everyone has died. You also have Research Stations and these are nice because there is one action that allows you to shuttle from station to station and that can get you closer to an infested area to have a chance to treat, cure and/or eradicate several or all cities. There are also Role Cards and pawns to match the color of your role. Each role has special duties that only that player can perform (see above with Medic and Dispatcher). You don't get to choose your color/role. Pandemic is for 2-4 players and there are 6 Role Cards so you won't have all 6 roles in game play at the same time. There is another extension that adds a 5th player.I know there is a lot more that can be said and I or someone else can try to answer your questions. I just played for the first time last night (4/13/19) and while playing the 2nd game I came to Amazon and we read descriptions for some the expansions. I immediately ordered Pandemic: The Cure--Experimental Meds and then about 2 hours later I ordered Pandemic: State Of Emergency (this introduces diseases/infections from animals). So as you can see this is how pleased I was with Pandemic and yes, we are still playing TTR...I will be posting some more reviews on those as well because I currently have 9 versions.I think I got infected with a board game virus but hey, what can I say; my family/friends still love games the old-fashioned way...totally unplugged, board games and card games around the table. On a side note I must share what happened during our game. My daddy called and my sister held the phone out so he could hear my niece and me playing. We had one part of the map covered and ready to explode with black Disease Cubes. My niece was trying to tell me how I could (as the Medic) take care of all the blacks. She said, "Auntie, if you just get rid of all the blacks we won't die! Can you just take care of all the blacks over there?" and she pointed to the area that was well infected AND we were trying to treat/cure some the disease so that we could remove some the black Disease Cubes off the board and continue game play. Later I dropped a Dorito on the map and I told my sister, "Shay-Bo, I think I just killed everyone in Moscow because a large UFO has landed on them." We are a Christian family that doesn't drink, smoke, etc. We just like to have good clean fun but I told my family if anyone was a fly on the wall during our game play they would have been questioning our integrity. We have already planned our next family game day for Good Friday and yes, it will be good!!