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A Milestone in Prostate Cancer Research: The Inspiring Success of the RESPOND Study

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In a monumental stride toward understanding and combating prostate cancer disparities, the RESPOND study has achieved a landmark victory by recruiting the largest cohort of African American men for prostate cancer research. This comes at a time when the need for such studies is more critical than ever, particularly given the disproportionate impact prostate cancer has on African American men.

Chasing Better Outcomes Amidst Challenges

Statistics reveal daunting disparities: African American men suffer from higher rates of prostate cancer with earlier onset and twice the mortality rate compared to other racial groups. Spearheaded by Dr. Christopher Haiman, a genetic epidemiologist at the University of Southern California (USC), the RESPOND study (Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Tumor Markers, and Social Stress) has made remarkable strides in recruiting over 12,600 volunteers, far surpassing its initial goals.

RESPOND
Dr. Christopher Haiman, a genetic epidemiologist at the University of Southern California, is the RESPOND study’s principal investigator.

This success didn’t come easy, especially as the study’s recruitment phase coincided with the dual upheavals of the COVID-19 pandemic and a national reckoning with racial injustice under the Black Lives Matter movement. Nevertheless, the determination and innovative approaches employed by the RESPOND team, including using sophisticated tools like genome-wide genotyping and next-generation sequencing, have not only kept the study on track but also enriched its potential outcomes.

Understanding the Layers: From Genetics to Social Stress

The broad, holistic design of RESPOND allows examination of various factors potentially contributing to the stark disparities seen in prostate cancer outcomes among African American men. Dr. Haiman pointed out the use of geospatial information systems (GIS) to scrutinize the impact of environmental and social stresses on these men. Also, the study is delving into the roles of structural factors such as residential redlining, which historically denied essential services and opportunities based on racial composition of neighborhoods, thus potentially contributing to health disparities.

The Power of Collaboration and Community Engagement

The success of RESPOND owes much to Dr. Ann Hamilton, who co-leads the recruitment efforts drawing from her extensive background in epidemiological studies. Their team’s strategy involved direct engagement with the community, highlighting not only the immediate benefits of participation but also the long-term impacts for future generations. Collaborations with advocacy groups and leveraging community trust were also key to addressing and overcoming the skepticism often associated with participation in medical research among African American communities.

RESPOND
University of Southern California epidemiologist and the RESPOND’s recruitment lead, Dr. Ann Hamilton, with Mr. Freddie Muse, Jr., a men’s health advocate, at a prostate health event in Los Angeles.

The Road Ahead: Data Analysis and Future Research

As RESPond shifts from recruitment to data analysis, the possibilities are promising. Dr. Haiman envisions a series of future studies that could look into treatment types and their effects on survival rates, the use of AI in detecting tumor signatures, and genetic and lifestyle factors contributing to prostate cancer risks among African American men.

Each step forward not only brings us closer to understanding the complex interplay of factors contributing to cancer disparities but also underscores the crucial need for tailored medical research that respects and responds to the unique needs of diverse populations.

A Beacon of Hope

RESPOND stands as a beacon of hope, not just for those battling prostate and other forms of cancers but for the medical research community at large. It exemplifies how perseverance, innovation, and community engagement can come together to pave the way for groundbreaking advancements in health and medicine.

The thorough engagement of over 12,600 African American men in this significant study not only marks a historic achievement but also sets the stage for profound impacts on public health policies and future research methodologies. Through their dedication, the RESPOND team is creating a legacy that will benefit many generations to come, truly embodying the ethos of doing ‘what is needed for future generations’.

A Moment of Reflection

As we move forward, it is crucial to reflect on the lessons learned from the RESPOND study – lessons about resilience, the power of community, and the imperative to continually bridge gaps in healthcare disparities. The journey of RESPOND is far from over, but its impacts will resonate for years to, shaping the contours of minority health research and policy.

The journey towards equitable health outcomes continues, and thanks to initiatives like RESPOND, we are another step closer to a future where health disparities are no longer a barrier to living long, healthy lives.


RESPOND study

Support & Further Reading
For further details on the RESPOND study and to support this critical research, please visit RESPOND Study Website. Together, we can make a difference in the lives of millions.

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.

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Beverages

Aim for Healthier Hydration with a Habit-Building Beverage

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Aim for Healthier Hydration with a Habit-Building Beverage

building

Aim for Healthier Hydration with a Habit-Building Beverage

(Family Features) Begin building tiny, healthier practices into routines you already have to help make it easier to establish habits you can stick to. This concept is called “habit stacking,” and it can help you improve habits from morning to night.

Consider those busy mornings when you need an on-the-go solution rather than opting for sugary foods and drinks, turn to Green Tea Berry Banana Smoothies that include unsweetened green tea. When incorporated as part of an overall healthy diet, unsweetened tea can support heart health.

This no-sugar-added recipe from Lipton, a proud national sponsor of the American Heart Association’s Life is Why campaign, can help you enjoy healthier mornings while checking emails or hydrating before heading to the office.

Choosing beverages with no added sugars can contribute to a healthy heart, according to the  American Heart Association, making these smoothies perfect for building into a morning routine. Because it’s predominantly water, which is needed to keep your body running at its best, unsweetened tea provides a delicious way to hydrate without ditching those healthier habits.

Visit Heart.org/eatsmart to find more habits that contribute to heart health.

Watch video to see how to make this recipe!

Green Tea Berry Banana Smoothies

Recipe courtesy of the American Heart Association
Servings: 4 (1 1/2 cups per serving)

  • 3          cups water
  • 8          single-serving green tea bags
  • 16        ounces frozen mixed berries (about 3 cups)
  • 2          medium bananas, peeled, cut in half and frozen
  • 1          cup fat-free plain Greek yogurt
  • 2          teaspoons fresh-grated peeled gingerroot (optional)
  • 2          teaspoons vanilla extract (optional)
  • 2          teaspoons chia or flax seeds (optional)
  1. In small saucepan over high heat, bring water to boil. Remove pan from heat. Submerge tea bags. Steep 4 minutes. Discard tea bags. Let tea mixture cool 30 minutes. Pour into pitcher. Refrigerate 2 hours, or until chilled.
  2. In food processor or blender, process tea, berries, bananas and yogurt until smooth. Add gingerroot and vanilla, if desired, and process until smooth. Pour into four glasses. Sprinkle with chia seeds, if desired.

Nutritional information per serving (without optional ingredients): 136 calories; 1 g total fat (0 g saturated fat, trans fat, polyunsaturated fat and monounsaturated fat); 3 mg cholesterol; 23 mg sodium; 29 g carbohydrates; 5 g fiber; 18 g total sugars (0 g added sugars); 8 g protein.


SOURCE:
American Heart Association

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recipes

Smart Starts for a Healthy Heart

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Healthy Heart

Heart Health: Improve hydration, skip added sugars with better-for-you beverages

(Family Features) How you start your morning can impact the rest of your day. If you’re looking to incorporate healthier choices into your morning routine, try a concept known as “habit stacking.” Building tiny, healthier habits into routines you already have, like enjoying a morning beverage or breakfast before you check your email instead of jumping right into the day’s tasks, can make it easier to stick to a new habit when it’s built into an existing routine.

If you already enjoy the routine of breakfast to start the day, consider swapping sugary drinks for beverages without added sugars like unsweetened green or black tea. When incorporated as part of an overall healthy diet, unsweetened tea can help support heart health.

If you need help getting started, Lipton, a proud national sponsor of the American Heart Association’s Life is Why campaign, created these easy-to-make, better-for-you tea recipes.

A small handful of ingredients makes a big splash in Green Tea Berry Banana Smoothies, ideal for an on-the-go breakfast. For a little refreshment any time of day, simple Sparkling Green Tea Cranberry Spritzers offer a solution with 0 grams of added sugars while non-alcoholic Green Tea Mojito Mocktails provide natural sweetness with 100% fruit juice.

Choosing beverages with no added sugars can contribute to a healthy heart, according to the American Heart Association, making these recipes perfect for daily habit stacking. Water is needed to keep your body running at its best, and because unsweetened tea is 99.5 % water, it provides a delicious way to help hydrate.

Discover more ways to improve daily routines at Heart.org/eatsmart.

Green Tea Berry Banana Smoothies

Recipe courtesy of the American Heart Association
Servings: 4 (1 1/2 cups per serving)

  • 3 cups water
  • 8 single-serving green tea bags
  • 16 ounces frozen mixed berries (about 3 cups)
  • 2 medium bananas, peeled, cut in half and frozen
  • 1 cup fat-free plain Greek yogurt
  • 2 teaspoons fresh-grated peeled gingerroot (optional)
  • 2 teaspoons vanilla extract (optional)
  • 2 teaspoons chia or flax seeds (optional)
  1. In small saucepan over high heat, bring water to boil. Remove pan from heat. Submerge tea bags. Steep 4 minutes. Discard tea bags. Let tea mixture cool 30 minutes. Pour into pitcher. Refrigerate 2 hours, or until chilled.
  2. In food processor or blender, process tea, berries, bananas and yogurt until smooth. Add gingerroot and vanilla, if desired, and process until smooth. Pour into four glasses. Sprinkle with chia seeds, if desired.

Nutritional information per serving (without optional ingredients): 136 calories; 1 g total fat (0 g saturated fat, trans fat, polyunsaturated fat and monounsaturated fat); 3 mg cholesterol; 23 mg sodium; 29 g carbohydrates; 5 g fiber; 18 g total sugars (0 g added sugars); 8 g protein.

Green Tea Mojito Mocktails

Recipe courtesy of the American Heart Association
Servings: 4 (1 1/2 cups per serving)

  • 4 cups water
  • 4 single-serving green tea bags
  • 32-40 sprigs fresh mint, plus additional for garnish, divided
  • 2 cups ice cubes
  • 1 cup 100% white grape juice
  • 1/2 cup fresh lime juice (about 4 medium limes)
  • 1 medium lime, cut into four wedges or lime zest twists (optional)
  1. In small saucepan over high heat, bring water to boil. Remove pan from heat. Submerge tea bags. Steep 4 minutes. Discard tea bags. Let tea mixture cool 30 minutes. Pour into pitcher. Refrigerate 2 hours, or until chilled.
  2. At serving time, add mint leaves to four glasses. Using muddler or wooden spoon, mash mint leaves several times to release juices. Don’t mash into pulp. Add ice.
  3. Stir white grape juice and lime juice into tea mixture. Pour into glasses. Garnish each with lime wedge and mint leaf.

Tip: To get more juice from citrus, before slicing, microwave fruit on high 30 seconds, or until warm. When cool enough to handle, use citrus reamer or handheld juice press to juice citrus.

Nutritional information per serving: 45 calories; 0 g total fat (0 g saturated fat, trans fat, polyunsaturated fat and monounsaturated fat); 0 mg cholesterol; 7 mg sodium; 13 g carbohydrates; 0 g fiber; 10 g total sugars (0 g added sugars); 1 g protein.

Sparkling Green Tea Cranberry Spritzers

Recipe courtesy of the American Heart Association
Servings: 4 (1 1/2 cups per serving)

  • 4 cups water
  • 4 single-serving green tea bags
  • 1 cup 100% cranberry juice or 100% cranberry-pomegranate juice
  • 2 cups ice cubes
  • 1/2 cup seltzer (flavored or plain) or low-sodium club soda, chilled
  • 4 orange slices or lime wedges (optional)
  1. In small saucepan over high heat, bring water to boil. Remove pan from heat. Submerge tea bags. Steep 4 minutes. Discard tea bags. Let tea mixture cool 30 minutes. Pour into pitcher. Stir in cranberry juice. Refrigerate 2 hours, or until chilled.
  2. At serving time, put ice cubes in four glasses. Pour tea mixture into glasses. Top each serving with seltzer. Garnish with orange slices.

Tip: To create cranberry-flavored ice cubes, fill ice cube tray with 100% cranberry juice and freeze.

Nutritional information per serving: 32 calories: 0 g total fat (0 g saturated fat, trans fat, polyunsaturated fat and monounsaturated fat); 0 mg cholesterol; 4 mg sodium; 8 mg carbohydrates; 0 g fiber; 8 g total sugars (0 g added sugars); 1 g protein.


SOURCE:
American Heart Association

https://stmdailynews.com/food-and-drink/

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Health

Sleep Apnea is More Than a Snore

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(Family Features) Snoring throughout the night. Gasping for air suddenly while sleeping. Feeling tired after a night of rest. These aren’t just signs of a poor night’s sleep – they could be symptoms of obstructive sleep apnea.

Sleep apnea is a serious sleep disorder characterized by a repetitive collapse of the airway during sleep. Most people with sleep apnea don’t even know they have it – in fact, 80% of people with sleep apnea in the United States are undiagnosed, according to research published in the “American Journal of Epidemiology.”

Experts from the American Academy of Sleep Medicine (AASM) recommend most adults get at least seven hours of sleep each night without waking frequently. If you have untreated sleep apnea, healthy, uninterrupted sleep can be hard to achieve. When the airway collapses or becomes blocked while you sleep, it causes you to wake briefly – maybe with a snore or gasp for air – to unblock the airway.

Untreated sleep apnea can contribute to long-term health problems, including hypertension (high blood pressure), heart disease, stroke, Type 2 diabetes and depression. Overall quality of life can also suffer. It can lead to a decline in mood, lower work productivity, difficulty concentrating and making decisions and an increased likelihood of getting into a traffic accident due to sleepiness.

The disorder may even affect your family and relationships; snoring or poor sleep due to sleep apnea can keep your family members up at night, affect your mood with others and impact your general decision-making. Consider this additional information about sleep apnea from Count on Sleep, a collaborative awareness program led by the AASM.

Signs and symptoms of OSA:

  • Snoring or noisy breathing
  • Stopping breathing while asleep
  • Waking up gasping or choking
  • Restless sleep or waking up tired and groggy after a full night’s sleep
  • Insomnia
  • Waking up frequently to use the bathroom
  • Having headaches in the morning
  • Feeling sleepy or falling asleep during the day
  • Having difficulty with memory or concentrating
  • Mood changes or irritability
  • Drowsy driving

Risk factors for OSA:

  • Overweight or obesity (BMI of more than 30)
  • High blood pressure
  • Neck size of more than 17 inches for men; 16 inches for women
  • Coronary artery disease (a type of heart disease) or heart attack
  • Atrial fibrillation or other heart rhythm problems
  • Congestive heart failure
  • Type 2 diabetes
  • Stroke
  • Daytime sleepiness

If you think you may have undiagnosed sleep apnea, talk to your doctor about your signs, symptoms, risk factors and concerns. If friends or family members exhibit these symptoms, urge them to talk to a doctor.

Your doctor may screen or test you for sleep apnea, which could include an at-home sleep test or sleep study at an accredited sleep center. If diagnosed, treatment options include continuous positive airway pressure (CPAP) therapy, oral appliance, surgery or lifestyle changes.

Learn more about how sleep apnea affects health and take a short quiz to see if you may be at risk at countonsleep.org.


Sleep Apnea Treatments

When followed properly, sleep apnea treatment improves breathing, sleepiness and quality of life. Some people may find the disorder improves through lifestyle changes such as losing weight, sleeping on their side or quitting smoking or drinking alcohol. Most of the time, however, other treatment options are necessary, such as:

CPAP
The most common and recognized treatment for sleep apnea, a CPAP machine provides a steady stream of air to keep your airway open throughout the night.

Oral appliance therapy
Similar to a mouthguard, an oral appliance can be worn at night to prevent the airway from collapsing by moving the jaw forward.

Surgery
If lifestyle changes, CPAP or oral appliance therapy don’t work, there are surgical options to treat sleep apnea. They include upper airway stimulation, which uses an implanted device to stimulate a nerve that controls the tongue, moving it forward while you sleep.

Photos courtesy of Shutterstock


SOURCE:
American Academy of Sleep Medicine

Our Lifestyle section on STM Daily News is a hub of inspiration and practical information, offering a range of articles that touch on various aspects of daily life. From tips on family finances to guides for maintaining health and wellness, we strive to empower our readers with knowledge and resources to enhance their lifestyles. Whether you’re seeking outdoor activity ideas, fashion trends, or travel recommendations, our lifestyle section has got you covered. Visit us today at https://stmdailynews.com/category/lifestyle/ and embark on a journey of discovery and self-improvement.

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