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Weekly U.S. influenza surveillance report : 2017-2018 influenza season week 42 ending October 20, 2018

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    All data are preliminary and may change as more reports are received.

    Synopsis: Influenza activity in the United States remains low. Influenza A(H1N1)pdm09, influenza A(H3N2), and influenza B viruses continue to co-circulate, with influenza A(H1N1)pdm09 viruses reported most commonly by public health laboratories during the most recent three weeks. Below is a summary of the key influenza indicators for the week ending October 20, 2018:

    • Viral Surveillance: Influenza A viruses have predominated in the United States since the beginning of July. The percentage of respiratory specimens testing positive for influenza in clinical laboratories was low.

    o Virus Characterization: The majority of influenza viruses characterized antigenically and genetically are similar to the cell-grown reference viruses representing the 2018–2019 Northern Hemisphere influenza vaccine viruses.

    o Antiviral Resistance: All viruses tested since late May show susceptibility to the antiviral drugs oseltamivir, zanamivir, and peramivir.

    • Influenza-like Illness Surveillance: The proportion of outpatient visits for influenza-like illness (ILI) remained low at 1.5%, which is below the national baseline of 2.2%. All regions reported ILI below their region-specific baseline level.

    • ILI State Activity Indictor Map: Puerto Rico and one state experienced low ILI activity; and New York City, the District of Columbia, and 49 states experienced minimal ILI activity..

    • Geographic Spread of Influenza: The geographic spread of influenza in four states was reported as local; the District of Columbia, Puerto Rico, the U.S. Virgin Islands and 42 states reported sporadic activity; four states reported no activity; and Guam did not report.

    • Pneumonia and Influenza Mortality: The proportion of deaths attributed to pneumonia and influenza (P&I) was below the system-specific epidemic threshold in the National Center for Health Statistics (NCHS) Mortality Surveillance System.

    • Influenza-associated Pediatric Deaths: No influenza-associated pediatric deaths were reported to CDC.

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