Life is the interplay between structure and energy, yet the role of energy deficiency in human
disease has been poorly explored by modern medicine. Since the mitochondria use
oxidative phosphorylation (OXPHOS) to convert dietary calories into usable energy,
generating reactive oxygen species (ROS) as a toxic by-product, I hypothesize that
mitochondrial dysfunction plays a central role in a wide range of age-related disorders and
various forms of cancer. Because mitochondrial DNA (mtDNA) is present in thousands of�…