Gnotobiotic techniques and their application to spacecraft fabrication.
PC Trexler�- Life Sciences and Space Research, 1964 - europepmc.org
Several colonies of rats and mice have been reared totally free of viable microorganisms,
some for over 10 years. A variety of other species including monkeys, dogs, sheep and
swine have been maintained under the same conditions for shorter periods. This operation
requires more precise control of microbic contamination than can be achieved by
conventional techniques. The necessary control was realized by the use of apparatus
termed" isolators". Obtaining sterility is a biological problem but its maintenance is an�…
some for over 10 years. A variety of other species including monkeys, dogs, sheep and
swine have been maintained under the same conditions for shorter periods. This operation
requires more precise control of microbic contamination than can be achieved by
conventional techniques. The necessary control was realized by the use of apparatus
termed" isolators". Obtaining sterility is a biological problem but its maintenance is an�…
[CITATION][C] Gnotobiotic techniques and their application to spacecraft fabrication(Gnotobiotic techniques developed to provide high order of sterility for fabrication of�…
PC TREXLER - 1964