Each year millions of papers are published reporting the results of medical research, making
it virtually impossible for clinicians to keep up to date with the latest developments. However,
it is important that clinical practice is based on the best available evidence and that effective
treatments should be introduced as quickly as possible for the benefit of patients. Systematic
reviews are different from traditional literature reviews because they aim to identify all
studies (published and unpublished) that address a specific question and their methodology�…