Multidrug-resistant Gram-negative bacteria: a product of globalization

PM Hawkey�- Journal of Hospital Infection, 2015 - Elsevier
Global trade and mobility of people has increased rapidly over the last 20 years. This has
had profound consequences for the evolution and the movement of antibiotic resistance
genes. There is increasing exposure of populations all around the world to resistant bacteria
arising in the emerging economies. Arguably the most important development of the last two
decades in the field of antibiotic resistance is the emergence and spread of extended-
spectrum β-lactamases (ESBLs) of the CTX-M group. A consequence of the very high rates�…