Radiation injury and neurogenesis
ML Monje, T Palmer�- Current opinion in neurology, 2003 - journals.lww.com
ML Monje, T Palmer
Current opinion in neurology, 2003•journals.lww.comProgressive learning and memory deficits following irradiation may be caused by the
accumulating hippocampal dysfunction that results from a long-term absence of normal
stem/progenitor activity. Here, the authors describe the nature of this stem cell dysfunction
and contemplate how restoration of stem/progenitor cell activity might be approached in
experimental models and, eventually, the clinic.
accumulating hippocampal dysfunction that results from a long-term absence of normal
stem/progenitor activity. Here, the authors describe the nature of this stem cell dysfunction
and contemplate how restoration of stem/progenitor cell activity might be approached in
experimental models and, eventually, the clinic.
Summary
Progressive learning and memory deficits following irradiation may be caused by the accumulating hippocampal dysfunction that results from a long-term absence of normal stem/progenitor activity. Here, the authors describe the nature of this stem cell dysfunction and contemplate how restoration of stem/progenitor cell activity might be approached in experimental models and, eventually, the clinic.
Lippincott Williams & Wilkins