Evaluation of immunohistochemistry and in situ hybridization methods for the detection of enteroviruses using infected cell culture samples

M Oikarinen, S Tauriainen, P Penttil�, J Keim…�- Journal of clinical�…, 2010 - Elsevier
BACKGROUND: Enterovirus infections are frequent in all age groups. In addition to acute
infections, they have been connected to chronic diseases such as cardiomyopathies and
type 1 diabetes. Based on this there is an increasing need for the reliable detection of
enteroviruses in different kinds of tissue samples. OBJECTIVES: The aim of this study was to
set up a test panel which can detect a wide range of different enteroviruses in paraffin-
embedded samples and fresh frozen samples using immunohistochemical and in situ�…