Differential expression profile of immunological cytokines in local ovary in patients with polycystic ovarian syndrome: analysis by flow cytometry
L Qin, W Xu, X Li, W Meng, L Hu, Z Luo, Y Wang…�- European Journal of�…, 2016 - Elsevier
Objective Immune dysregulation may play an important role in the pathogenesis of
polycystic ovary syndrome (PCOS). The purpose of this study was to investigate the Th1 and
Th2-related cytokine profile in local ovary of women with PCOS. Study Design The T
lymphocytes of follicular fluid (FF) were obtained at the time of oocyte retrieval before in-vitro
fertilization (IVF) in woman with or without PCOS. After culturing with PMA, Ionomycin and
Golgi stop agent, cells were detected for the intracellular cytokine production by flow�…
polycystic ovary syndrome (PCOS). The purpose of this study was to investigate the Th1 and
Th2-related cytokine profile in local ovary of women with PCOS. Study Design The T
lymphocytes of follicular fluid (FF) were obtained at the time of oocyte retrieval before in-vitro
fertilization (IVF) in woman with or without PCOS. After culturing with PMA, Ionomycin and
Golgi stop agent, cells were detected for the intracellular cytokine production by flow�…