Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder
JZ Konarski, SH Kennedy, ZV Segal, MA Lau…�- Journal of Psychiatry and�…, 2009 - jpn.ca
Background: Longitudinal neuroimaging investigations of antidepressant treatment offer the
opportunity to identify potential baseline biomarkers associated with poor outcome.
Methods: To explore the neural correlates of nonresponse to cognitive behavioural therapy
(CBT) or venlafaxine (VEN), we compared pretreatment (18) F-fluoro-2-deoxy-d-glucose
positron emission tomography scans of participants with major depressive disorder
responding to either 16 weeks of CBT (n= 7) or VEN treatment (n= 9) with treatment�…
opportunity to identify potential baseline biomarkers associated with poor outcome.
Methods: To explore the neural correlates of nonresponse to cognitive behavioural therapy
(CBT) or venlafaxine (VEN), we compared pretreatment (18) F-fluoro-2-deoxy-d-glucose
positron emission tomography scans of participants with major depressive disorder
responding to either 16 weeks of CBT (n= 7) or VEN treatment (n= 9) with treatment�…