[HTML][HTML] In vivo imaging of neurotransmitter systems using radiolabeled receptor ligands

LS Kegeles, JJ Mann�- Neuropsychopharmacology, 1997 - Elsevier
In vivo functional brain imaging, including global blood flow, regional cerebral blood flow
(rCBF), measured with positron emission tomography (PET) and single photon emission
computed tomography (SPECT), and regional cerebral metabolic rate (rCMR) measured
with deoxyglucose PET, have been widely used in studies of psychiatric disorders. These
studies have found modest differences and required large numbers of patients. Activation
studies using rCBF or rCMR as indices of neuronal activity are more sensitive because�…