This study examined the influence of reward sensitivity (BAS) and threat sensitivity (FFFS) on alcohol use and investigated the mediating role of dispositional coping in this relationship. Specifically, it was proposed that FFFS may exert indirect effects on alcohol use by promoting use of maladaptive coping strategies (e.g. avoidance-focused coping, emotion-focused coping). In contrast, it was expected that BAS would have a direct effect on alcohol use not mediated by coping. The final sample comprised of 337 participants (age, M=26.95, SD=10.61) who completed questionnaire measures of alcohol use, BAS/FFFS, and coping. Path analyses controlling for measurement error (AMOS), revealed significant direct effects of BAS and indirect effects of FFFS on alcohol use. Specifically, the relationship between FFFS and alcohol use was found to be mediated by avoidance-focused coping and emotion-focused coping. It was concluded that the relationship between FFFS and alcohol use can be partly explained by use of maladaptive coping strategies, suggesting that reducing reliance on avoidance-focused, while increasing use of problem-focused and emotion-focused coping may be an effective intervention for individuals with heightened threat sensitivity (i.e. high FFFS).