The purpose of this study was to examine the relationship between job satisfaction and mental health. The statistics include all employees of two industrial companies in the city of Ardabil. The sample of 90 people was selected randomly for the study. They were asked to complete Birfield job satisfaction and Ruth questionnaire and Goldberg‘s general health scale. Data was analysis using multiple regressions and t-test. Finding of the research indicated that there was a positive relationship between job unsatisfaction employees and global index of mental health, social action and depression. It was found that employed women than employed men are more satisfied with their jobs. In addition, workers who have a longer history in their jobs have much job satisfaction. The results of this study, confirmed previous findings on the role of job satisfaction in the provision of mental health workers, especially to improve social relations and reduce depression.