Chronic work stress and marital dissolution increase risk of posttrial mortality in men from the Multiple Risk Factor Intervention Trial

KA Matthews, BB Gump�- Archives of Internal Medicine, 2002 - jamanetwork.com
Background Acute life stressors can trigger premature death, but the role of more enduring,
chronic stressors is less clear. We evaluated men's mortality risk associated with number of
different work stressors and marital dissolution during the Multiple Risk Factor Intervention
Trial (MRFIT). Methods Men without definite evidence of coronary heart disease (CHD) at
study entry but with above-average risk for CHD mortality based on blood pressure, serum
cholesterol levels, and/or cigarette smoking were recruited into MRFIT. Survivors at the end�…