[PDF][PDF] Validation of nitrogen-13-ammonia tracer kinetic model for quantification of myocardial blood flow using PET

O Muzik, RSB Beanlands, GD Hutchins…�- Journal of Nuclear�…, 1993 - Soc Nuclear Med
O Muzik, RSB Beanlands, GD Hutchins, TJ Mangner, N Nguyen, M Schwaiger
Journal of Nuclear Medicine, 1993Soc Nuclear Med
The purpose of this study was to validate the three compartment kinetic model for myocardial
blood flow measurements using �€ 3N-ammoniadeveloped at our insti tution. Blood flow
estimates with �€ 3N-ammoniawere com pared to those obtained with �€ 50-waterin the dog
model. Both PET flow measurements were correlated with micro sphere determined blood
flows over a wide flow range.
The purpose of this study was to validate the three compartment kinetic model for myocardial blood flow measurements using �€ 3N-ammoniadeveloped at our insti tution. Blood flow estimates with �€ 3N-ammoniawere com pared to those obtained with �€ 50-waterin the dog model. Both PET flow measurements were correlated with micro sphere determined blood flows over a wide flow range.
Society of Nuclear Medicine and Molecular Imaging