Functional gastrointestinal disorders among people with sleep disturbances: a population-based study
SS Vege, GR Locke III, AL Weaver, SA Farmer…�- Mayo Clinic�…, 2004 - Elsevier
SS Vege, GR Locke III, AL Weaver, SA Farmer, LJ Melton III, NJ Talley
Mayo Clinic Proceedings, 2004•ElsevierOBJECTIVE To determine whether unexplained gastrointestinal (GI) symptoms are more
common in people with self-reported sleep disturbance. PARTICIPANTS AND METHODS
From November 1988 to June 1994, valid self-report questionnaires were mailed to age-and
sex-stratified random samples of Olmsted County, Minnesota, residents aged 20 to 95 years.
RESULTS Of 2269 study participants (74% response rate), 52% were women (mean age,
45.0 years). The overall age-and sex-adjusted prevalence of sleep disturbance per 100�…
common in people with self-reported sleep disturbance. PARTICIPANTS AND METHODS
From November 1988 to June 1994, valid self-report questionnaires were mailed to age-and
sex-stratified random samples of Olmsted County, Minnesota, residents aged 20 to 95 years.
RESULTS Of 2269 study participants (74% response rate), 52% were women (mean age,
45.0 years). The overall age-and sex-adjusted prevalence of sleep disturbance per 100�…
OBJECTIVE
To determine whether unexplained gastrointestinal (GI) symptoms are more common in people with self-reported sleep disturbance.
PARTICIPANTS AND METHODS
From November 1988 to June 1994, valid self-report questionnaires were mailed to age- and sex-stratified random samples of Olmsted County, Minnesota, residents aged 20 to 95 years.
RESULTS
Of 2269 study participants (74% response rate), 52% were women (mean age, 45.0 years). The overall age- and sex-adjusted prevalence of sleep disturbance per 100 population was 13.5% (95% confidence interval [CI], 11.7%-15.3%). Among study participants with sleep disturbance, the prevalence of irritable bowel syndrome (IBS) was 33.3% (95% CI, 26.0%-40.5%) and the prevalence of frequent dyspepsia (FD) was 21.3% (95% CI, 14.4%-28.2%). After adjusting for age, sex, and somatization score, IBS was significantly more common in those with sleep disturbance (odds ratio, 1.6; 95% CI, 1.1-2.2), but the univariate association with FD was no longer statistically significant (odds ratio, 1.3; 95% CI, 0.9-1.9).
CONCLUSIONS
Both IBS and FD are prevalent in those with self-reported sleep disturbance. Sleep disturbance was independently associated with IBS but not FD in the general population.
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