Immunocytochemical localization of the endogenous benzodiazepine ligand octadecaneuropeptide (ODN) in the rat brain
MC Tonon, L D�sy, P Nicolas, H Vaudry, G Pelletier�- Neuropeptides, 1990 - Elsevier
In order to study the morphological localization of the endogenous benzodiazepine ligand
octadecaneuropeptide (ODN) in rat brain, we have developed antibodies against this
peptide. Using a radioimmunoassay for ODN, we have observed that synthetic ODN and
serial dilutions of several brain areas gave parallel displacement curves. By light
microscope immunocytochemistry, ODN-immunoreactive material was only detected in glial
and ependymal cells. Immunolabelled cells were found in high concentrations in the�…
octadecaneuropeptide (ODN) in rat brain, we have developed antibodies against this
peptide. Using a radioimmunoassay for ODN, we have observed that synthetic ODN and
serial dilutions of several brain areas gave parallel displacement curves. By light
microscope immunocytochemistry, ODN-immunoreactive material was only detected in glial
and ependymal cells. Immunolabelled cells were found in high concentrations in the�…