[BOOK][B] Androgen action in prostate cancer
D Tindall, J Mohler - 2009 - books.google.com
Androgens are critical regulators of prostate differentiation and function, as well as prostate
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment
for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the
androgen receptor (AR), a nuclear receptor transcription factor. Historically, the gene
expression program mediated by the AR has been poorly understood. However, recent
gene expression profiling and more traditional single-gene characterization studies have�…
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment
for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the
androgen receptor (AR), a nuclear receptor transcription factor. Historically, the gene
expression program mediated by the AR has been poorly understood. However, recent
gene expression profiling and more traditional single-gene characterization studies have�…
[BOOK][B] Androgen action in prostate cancer
J Mohler, D Tindall - 2009 - Springer
Androgens are critical regulators of prostate differentiation and function, as well as prostate
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment
for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the
androgen receptor (AR), a nuclear receptor transcription factor.Historically, the gene
expression program mediated by the AR has been poorly understood. However, recent
gene expression profiling and more traditional single-gene characterization studies have�…
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment
for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the
androgen receptor (AR), a nuclear receptor transcription factor.Historically, the gene
expression program mediated by the AR has been poorly understood. However, recent
gene expression profiling and more traditional single-gene characterization studies have�…