Heart disease in the world has increased every year. Compensation for the work of the heart on the body causes a decrease in the patient’s activity which has an impact on sexual function. The purpose of this study was to analyse the effect of supportive educative cardiac rehabilitation phase 3 (SE-CRP3) on male sexual dysfunction (SD) among patients with Chronic Heart Disease (CHD). A quasi-experiment study was undertaken on August 2019. Sixty respondents was recruited by purposive sampling technique and divided into intervention and control groups. International Index of Erectile Function Questionnaire (IIEF) was used to obtained the data about sexual function. Then, we analysed the data using independent samples t-test and paired samples t-test. We found a significant difference between pre and post intervention in the intervention group (p= 0.039) with mean of sexual dysfunction (18.97 to 19.93). In addition, there was no significant difference between pre and post in the control group (p= 0.152) and no differences in the both groups after the intervention of SE-CRP3 (p= 0.568). SE-CRP3 therapy has an impact on sexual function among patients with CHD. This may be considered by nurses as an additional intervention in patients with CHD. Observations on the related variables can be considered.