Reduced thalamic volume in high-functioning individuals with autism
KD Tsatsanis, BP Rourke, A Klin, FR Volkmar…�- Biological�…, 2003 - Elsevier
BACKGROUND: In this study, specific consideration is given to a role for the thalamus in
autism. METHODS: A volumetric analysis of the thalamus was conducted using magnetic
resonance imaging, based on segmentation of continuous 1.2 mm3 coronal images. The
sample consisted of 12 high-functioning individuals with autism, mean age of 21.0 years
(SD= 10.4) and mean IQ of 106.4 (SD= 18.3). Normal control subjects were selected to
match this group; the mean age was 18.1 years (SD= 6.3); mean IQ was 108.8 (SD= 15.6)�…
autism. METHODS: A volumetric analysis of the thalamus was conducted using magnetic
resonance imaging, based on segmentation of continuous 1.2 mm3 coronal images. The
sample consisted of 12 high-functioning individuals with autism, mean age of 21.0 years
(SD= 10.4) and mean IQ of 106.4 (SD= 18.3). Normal control subjects were selected to
match this group; the mean age was 18.1 years (SD= 6.3); mean IQ was 108.8 (SD= 15.6)�…