[HTML][HTML] A novel heterozygous MKRN3 nonsense mutation in a Chinese girl with idiopathic central precocious puberty: a case report
M Liu, L Fan, CX Gong�- Medicine, 2020 - journals.lww.com
Interventions: The girl has been treated with a GnRH analog (3.75 mg every 4 wks) for 1
year and 5 months. Outcomes: The puberty signs have since not progressed during the
follow-up period, which indicates that the GnRH analogs treatment is effective. Lessons: This
case was obese companied with IGT at the baseline assessment and exhibited stronger
LH/FSH response to GnRH stimulation test. Therefore, clinicians should highlight the
importance of weight management and the long-term follow-up to monitor the adverse�…
year and 5 months. Outcomes: The puberty signs have since not progressed during the
follow-up period, which indicates that the GnRH analogs treatment is effective. Lessons: This
case was obese companied with IGT at the baseline assessment and exhibited stronger
LH/FSH response to GnRH stimulation test. Therefore, clinicians should highlight the
importance of weight management and the long-term follow-up to monitor the adverse�…