HPA function in adolescence: role of sex hormones in its regulation and the enduring consequences of exposure to stressors
CM McCormick, IZ Mathews�- Pharmacology Biochemistry and Behavior, 2007 - Elsevier
The hypothalamic–pituitary–adrenal (HPA) axis is one of the physiological systems involved
in coping with stressors. There are functional shifts in the HPA axis and its regulation by sex
hormones over the lifespan that allow the animal to meet the challenges of the internal and
external environment that are specific to each stage of development. Sex differences in HPA
function emerge over adolescence, a phenomenon reflecting the concomitant initiation of
regulatory effects of sex hormones. The focus of this review is recent research on differences�…
in coping with stressors. There are functional shifts in the HPA axis and its regulation by sex
hormones over the lifespan that allow the animal to meet the challenges of the internal and
external environment that are specific to each stage of development. Sex differences in HPA
function emerge over adolescence, a phenomenon reflecting the concomitant initiation of
regulatory effects of sex hormones. The focus of this review is recent research on differences�…