Introduction We have previously identified sex-specific differences in the fetal-placental
response to cortisol. Our recent studies suggest that this differential response to cortisol is
driven by differences in glucocorticoid receptor (GR) protein function rather than through
changes in gene transcription or protein expression. Methods This study was designed to
define whether the human placenta expresses different isoforms of the GR and whether
expression was altered by fetal sex and maternal asthma. Asthma and non-asthma pregnant�…