Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients�…
JM Williams, JH Greenslade, JV McKenzie, K Chu…�- Chest, 2017 - Elsevier
Background A proposed revision of sepsis definitions has abandoned the systemic
inflammatory response syndrome (SIRS), defined organ dysfunction as an increase in total
Sequential Organ Function Assessment (SOFA) score of≥ 2, and conceived “qSOFA”(quick
SOFA) as a bedside indicator of organ dysfunction. We aimed to (1) determine the
prognostic impact of SIRS,(2) compare the diagnostic accuracy of SIRS and qSOFA for
organ dysfunction, and (3) compare standard (Sepsis-2) and revised (Sepsis-3) definitions�…
inflammatory response syndrome (SIRS), defined organ dysfunction as an increase in total
Sequential Organ Function Assessment (SOFA) score of≥ 2, and conceived “qSOFA”(quick
SOFA) as a bedside indicator of organ dysfunction. We aimed to (1) determine the
prognostic impact of SIRS,(2) compare the diagnostic accuracy of SIRS and qSOFA for
organ dysfunction, and (3) compare standard (Sepsis-2) and revised (Sepsis-3) definitions�…