Postprandial dynamics and response of fibroblast growth factor 21 in older adults

C Herpich, U Ha�, B Kochlik, K Franz, T Laeger…�- Clinical Nutrition, 2021 - Elsevier
Background & aims Fibroblast growth factor 21 (FGF21) plays a pivotal role in glucose and
lipid metabolism and has been proposed as a longevity hormone. However, elevated
plasma FGF21 concentrations are paradoxically associated with mortality in higher age and
little is known about the postprandial regulation of FGF21 in older adults. In this parallel
group study, we investigated postprandial FGF21 dynamics and response in older (65–85
years) compared to younger (18–35 years) adults following test meals with varying�…