Randomized trial of harp therapy during in vitro fertilization–embryo transfer

EM Murphy, J Nichols, SG Somkuti…�- Journal of Evidence�…, 2014 - journals.sagepub.com
EM Murphy, J Nichols, SG Somkuti, M Sobel, A Braverman, LI Barmat
Journal of Evidence-Based Complementary & Alternative Medicine, 2014journals.sagepub.com
Objective: This study evaluated whether harp therapy reduces levels of stress and improves
clinical outcomes in patients undergoing embryo transfer. Design: This prospective
randomized trial enrolled 181 women undergoing embryo transfer, who were randomized to
harp therapy during embryo transfer or standard treatment. Patients underwent standardized
psychological testing and physiologic assessment of stress. Setting: The study was
conducted in a reproductive medicine practice. Results: No statistically significant�…
Objective
This study evaluated whether harp therapy reduces levels of stress and improves clinical outcomes in patients undergoing embryo transfer.
Design
This prospective randomized trial enrolled 181 women undergoing embryo transfer, who were randomized to harp therapy during embryo transfer or standard treatment. Patients underwent standardized psychological testing and physiologic assessment of stress.
Setting
The study was conducted in a reproductive medicine practice.
Results
No statistically significant differences were found in the heart and respiratory rates, nor was there a significant difference in event-based anxiety at baseline. Harp therapy had a significantly larger decrease in state anxiety from pre– to post–embryo transfer. Clinical pregnancy was 53% versus 48% for the harp therapy and standard treatment groups, respectively.
Conclusion
Harp therapy decreases state, or event-based, anxiety, significantly lowering state scores posttransfer and having a positive effect on acute levels of stress. There was an increased pregnancy rate, but larger sample sizes are needed to evaluate whether harp therapy has an effect on clinical outcomes.
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