Endothelial shear stress and plaque erosion: a computational fluid dynamics and optical coherence tomography study
E Yamamoto, V Thondapu, E Poon, T Sugiyama…�- JACC: Cardiovascular�…, 2019 - jacc.org
JACC: Cardiovascular Imaging, 2019•jacc.org
Acute coronary thrombosis with plaque erosion is responsible for about one-third of patients
with acute coronary syndromes. The relationship between endothelial shear stress (ESS)
and plaque erosion has not been systematically studied in patients so far.A total of 18 acute
coronary syndrome patients with plaque erosion were selected. Patients with side branches
(> 2 mm) were excluded. After optical coherence tomography (OCT)-based arterial
reconstruction, ESS, endothelial shear stress gradient (ESSG), and oscillatory shear index�…
with acute coronary syndromes. The relationship between endothelial shear stress (ESS)
and plaque erosion has not been systematically studied in patients so far.A total of 18 acute
coronary syndrome patients with plaque erosion were selected. Patients with side branches
(> 2 mm) were excluded. After optical coherence tomography (OCT)-based arterial
reconstruction, ESS, endothelial shear stress gradient (ESSG), and oscillatory shear index�…
Acute coronary thrombosis with plaque erosion is responsible for about one-third of patients with acute coronary syndromes. The relationship between endothelial shear stress (ESS) and plaque erosion has not been systematically studied in patients so far.
A total of 18 acute coronary syndrome patients with plaque erosion were selected. Patients with side branches (> 2 mm) were excluded. After optical coherence tomography (OCT)-based arterial reconstruction, ESS, endothelial shear stress gradient (ESSG), and oscillatory shear index (OSI) were calculated in every 0.25-mm segment.
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