Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study
ND Volkow, GJ Wang, L Maynard, JS Fowler…�- Psychiatry Research�…, 2002 - Elsevier
Imaging studies in patients with Type II alcohol dependence have revealed significant
reductions in dopamine (DA) D2 receptor availability. Here we assessed the effects of
alcohol detoxification in DA D2 receptors in alcoholic subjects. We evaluated 14 patients
with Type II alcohol dependence tested within 6 weeks of detoxification and then re-tested 1–
4 months later while alcohol free. The comparison group comprised 11 healthy controls. PET
was used with [11C] raclopride to measure DA D2 receptors. Eight alcoholics and all control�…
reductions in dopamine (DA) D2 receptor availability. Here we assessed the effects of
alcohol detoxification in DA D2 receptors in alcoholic subjects. We evaluated 14 patients
with Type II alcohol dependence tested within 6 weeks of detoxification and then re-tested 1–
4 months later while alcohol free. The comparison group comprised 11 healthy controls. PET
was used with [11C] raclopride to measure DA D2 receptors. Eight alcoholics and all control�…