Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis
Obstetrics & Gynecology, 2010•journals.lww.com
OBJECTIVE: To estimate the effect of low-dose aspirin started in early pregnancy on the
incidence of preeclampsia and intrauterine growth restriction (IUGR). DATA SOURCES: A
systematic review and meta-analysis were performed through electronic database searches
(PubMed, Cochrane, Embase). METHODS OF STUDY SELECTION: Randomized controlled
trials of pregnant women at risk of preeclampsia who were assigned to receive aspirin or
placebo (or no treatment) were reviewed. Secondary outcomes included IUGR, severe�…
incidence of preeclampsia and intrauterine growth restriction (IUGR). DATA SOURCES: A
systematic review and meta-analysis were performed through electronic database searches
(PubMed, Cochrane, Embase). METHODS OF STUDY SELECTION: Randomized controlled
trials of pregnant women at risk of preeclampsia who were assigned to receive aspirin or
placebo (or no treatment) were reviewed. Secondary outcomes included IUGR, severe�…
OBJECTIVE:
To estimate the effect of low-dose aspirin started in early pregnancy on the incidence of preeclampsia and intrauterine growth restriction (IUGR).
DATA SOURCES:
A systematic review and meta-analysis were performed through electronic database searches (PubMed, Cochrane, Embase).
METHODS OF STUDY SELECTION:
Randomized controlled trials of pregnant women at risk of preeclampsia who were assigned to receive aspirin or placebo (or no treatment) were reviewed. Secondary outcomes included IUGR, severe preeclampsia and preterm birth. The effect of aspirin was analyzed as a function of gestational age at initiation of the intervention (16 weeks of gestation or less, 16 weeks of gestation or more).
Lippincott Williams & Wilkins