Automatic processing and interpretation of DNA distributions: comparison of several techniques
DA Johnston, RA White, B Barlogie�- Computers and Biomedical Research, 1978 - Elsevier
There exist a large number of apparently different methods for interpreting the distribution of
DNA content in a population of cells as measured by an impulse cytophotometer (FMF).
Equations are derived to provide a model of the observed numbers of cells with a given DNA
content. Methods are described to compute the “ideal” distribution of cells necessary to find
the number of cells in G 1, S and G 2+ M phase. A comparison is made of several standard
methods for computing the cell age distribution. The methods are shown to be formally�…
DNA content in a population of cells as measured by an impulse cytophotometer (FMF).
Equations are derived to provide a model of the observed numbers of cells with a given DNA
content. Methods are described to compute the “ideal” distribution of cells necessary to find
the number of cells in G 1, S and G 2+ M phase. A comparison is made of several standard
methods for computing the cell age distribution. The methods are shown to be formally�…