Effect of vitamin D3 supplementation in pregnancy on risk of pre-eclampsia–Randomized controlled trial

AM Ali, A Alobaid, TN Malhis, AF Khattab�- Clinical nutrition, 2019 - Elsevier
Background Vitamin D plays pivotal role in decidualization and implantation of the placenta.
Recent researches have shown that low level of vitamin D3 “25-hydroxyvitamin D (25 [OH]
D)” in serum is a risk factor for pre-eclampsia. Latest evidence supports role of vitamin D3
deficiency treatment in reducing the risk of pre-eclampsia. The aim of this study is to
determine the effect of antenatal supplementation of vitamin D3 on the risk of pre-eclampsia
and to explore the dose effect in attaining the vitamin D3 normal level. Method An open�…